西多福韦水合物（1:2）

西多福韦水合物（1:2）（CAS 149394-66-1）的公开数据库记录，列此仅供独立核对。

物理形态与操作说明

• Solid
• Fluffy white powder
• White crystalline powder
• Aqueous solubility >=170 mg/ml @ pH 6-8
• log Kow = -3.3 @ pH 7.1
• It is recommended that cidofovir admixtures be administered within 24 hours of preparation and that refrigeration or freezer storage not be used to extend this 24 hour limit.

公开数据库收录的理化数据

这个物质在各数据库里的编号

数据库记载的用途

• Preparation: A. Holy et al., EP 253412; eidem, US 5142051 (1988, 1992 both to Ceskoslov. Akad, Ved; Rega Inst.) ... .
• For the treatment of CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS)
• Cidofovir is a nucleoside analogue and antiviral agent which is used in therapy of serious cytomegalovirus infections in immunocompromised patients. Cidofovir has been associated with mild-to-moderate serum aminotransferase elevations during intravenous therapy, but has not been convincingly linked to cases of clinically apparent acute liver injury.
• Breast Feeding; Lactation; Milk, Human; Anti-Infective Agents; Antiviral Agents
• Cidofovir is used for the treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS).
• Cidofovir has been used for the management of acyclovir-resistant herpes simplex virus (HSV-1 and HSV-2) infections in immunocompromised patients.

它在各数据库里的别名

Cidofovir; 113852-37-2; Vistide; HPMPC; Cidofovir anhydrous; (S)-HPMPC; anhydrous cidofovir; GS-504; (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine; DTXSID3043734; GS 0504; GS504; GS-0504; 768M1V522C; NSC-742135; 1-[(S)-3-hydroxy-2-(phosphonomethoxy)propyl]cytosine

计算机算出的分子描述符

数据库摘要

Cidofovir hydrate (1:2) · CAS 149394-66-1 · C8H14N3O6P. UNII 768M1V522C. 熔点: 480; 熔点: 260 °C (dec); 熔点: 480 °C.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。