盐酸地尔硫卓

Description

Diltiazem HCl · CAS 33286-22-5 · C22H27ClN2O4S. UNII OLH94387TE.

Identification

CAS Registry Number	33286-22-5
PubChem CID	62920
Molecular formula	C22H27ClN2O4S
IUPAC name	[(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate;hydrochloride
UNII (FDA)	OLH94387TE

Computed Descriptors

Molecular Weight	451.0
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	7
Exact Mass	450.1380062
Monoisotopic Mass	450.1380062
Topological Polar Surface Area	84.4
Heavy Atom Count	30
Formal Charge	0
Complexity	565

Physical description & handling notes

• 196.1 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H302 (99.2%), H361 (10.1%)

Documented Uses

• For the treatment of hypertension.
• Breast Feeding; Lactation; Milk, Human; Antihypertensive Agents; Calcium Channel Blockers; Antiarrhythmics; Vasodilator Agents
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
• A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
• Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
• Drugs used to cause dilation of the blood vessels.

Synonyms

Diltiazem hydrochloride; 33286-22-5; Diltiazem HCl; Adizem; Dilzem; Dilzene; Masdil; Altiazem; Deltazen; Diladel; Dilpral; Dilrene; Tildiem; Cardizem LA; Britiazim; Zilden

Frequently Asked Questions

What are the CAS number and molecular formula of Diltiazem HCl?

CAS 33286-22-5; molecular formula C22H27ClN2O4S; molecular weight — g/mol.

What other names is Diltiazem HCl known by?

Diltiazem hydrochloride, 33286-22-5, Diltiazem HCl, Adizem, Dilzem, Dilzene.

Is Diltiazem HCl classified as hazardous?

Hazard statements reported: H302, H361.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.