盐酸多奈哌齐

盐酸多奈哌齐（CAS 110119-84-1）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

物理形态与操作说明

• 196.6 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

这个物质在各数据库里的编号

数据库记载的用途

• For the palliative treatment of mild to moderate dementia of the Alzheimer's type.
• Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms.
• Cholinesterase Inhibitors [MoA]; Cholinesterase Inhibitor [EPC]
• Donepezil is metabolized by CYP 450 isoenzymes 2D6 and 3A4 in the liver and also undergoes glucuronidation. The main metabolite, 6-O-desmethyl donepezil, has been reported to inhibit AChE to the same extent as donepezil in vitro. Route of Elimination: Donepezil is both excreted in the urine intact and extensively metabolized to four major metabolites, two of which are known to be active, and a number of minor metabolites, not all of which have been identified. Half Life: 70 hours

它在各数据库里的别名

Donepezil hydrochloride; 120011-70-3; Donepezil HCl; BNAG; Aricept ODT; E-2020; E2020; ADLARITY; DTXSID0046698; Aricept Evess; NSC-737535; NSC-758882; 3O2T2PJ89D; DTXCID8026698; 1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hcl; NAMZARIC COMPONENT DONEPEZIL HYDROCHLORIDE

计算机算出的分子描述符

数据库摘要

Donepezil hydrochloride · CAS 110119-84-1 · C24H30ClNO3. UNII 3O2T2PJ89D.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。