盐酸柔红霉素

Description

daunomycin hydrochloride · CAS 23541-50-6 · C27H29NO10.HCl. UNII UD984I04LZ.

Identification

CAS Registry Number	23541-50-6
PubChem CID	62770
Molecular formula	C27H29NO10.HCl
IUPAC name	(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride
UNII (FDA)	UD984I04LZ

Computed Descriptors

Molecular Weight	564.0
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	4
Exact Mass	563.1558238
Monoisotopic Mass	563.1558238
Topological Polar Surface Area	186
Heavy Atom Count	39
Formal Charge	0
Complexity	960

Physical description & handling notes

• Daunorubicin hydrochloride appears as orange-red powder. Thin red needles decomposing at 188-190 °C. An anti-cancer drug.
• 370 to 374 °F (decomposes) (NTP, 1992)
• Soluble (NTP, 1992)

GHS Hazard Classification

Reported hazard statements	H301 (70.2%), H302 (29.8%), H334 (66.3%), H341 (32.7%), H351 (99%), H360 (32.7%)

Documented Uses

• For remission induction in acute nonlymphocytic leukemia (myelogenous, monocytic, erythroid) of adults and for remission induction in acute lymphocytic leukemia of children and adults.
• Breast Feeding; Lactation; Milk, Human; Antineoplastic Agents; Anthracyclines; Antibiotics, Antineoplastic; Topoisomerase II Inhibitors
• Daunorubicin hydrochloride is approved to be used with other drugs as remission induction therapy to treat:
• • Acute lymphoblastic leukemia in adults and children.
• • Acute myeloid leukemia in adults.
• It is also being studied in the treatment of other types of cancer.

Synonyms

DAUNORUBICIN HYDROCHLORIDE; 23541-50-6; DAUNORUBICIN HCL; Daunomycin hydrochloride; Daunoblastina; RP 13057 hydrochloride; Rubidomycin hydrochloride; Ondena; Daunomycin chlorohydrate; Daunomycin, hydrochloride; RP-13057 Hydrochloride; Daunoblastin; NDC 0082-4155; DTXSID0033382; Daunorubicin (as hydrochloride); UD984I04LZ

Frequently Asked Questions

What are the CAS number and molecular formula of daunomycin hydrochloride?

CAS 23541-50-6; molecular formula C27H29NO10.HCl; molecular weight — g/mol.

What other names is daunomycin hydrochloride known by?

DAUNORUBICIN HYDROCHLORIDE, 23541-50-6, DAUNORUBICIN HCL, Daunomycin hydrochloride, Daunoblastina, RP 13057 hydrochloride.

Is daunomycin hydrochloride classified as hazardous?

Hazard statements reported: H301, H302, H334, H341, H351.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.