地红霉素

Description

Dirithromycin · CAS 62013-04-1 · C42H78N2O14. UNII 1801D76STL. LogP: 1.6.

Identification

CAS Registry Number	62013-04-1
PubChem CID	6473883
Molecular formula	C42H78N2O14
IUPAC name	(1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,15R,17S)-9-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-3-ethyl-2,10-dihydroxy-7-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-15-(2-methoxyethoxymethyl)-2,6,8,10,12,17-hexamethyl-4,16-dioxa-14-azabicyclo[11.3.1]heptadecan-5-one
UNII (FDA)	1801D76STL

Computed Descriptors

Molecular Weight	835.1
XLogP3	4.2
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	16
Rotatable Bond Count	12
Exact Mass	834.54530517
Monoisotopic Mass	834.54530517
Topological Polar Surface Area	196
Heavy Atom Count	58
Formal Charge	0

Physical & Chemical Properties

LogP	1.6

Physical description & handling notes

• Poor
• 284.2 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 282.31 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H317 (100%)

Documented Uses

• For the treatment of the following mild-to-moderate infections caused by susceptible strains of microorganisms: acute bacterial exacerbations of chronic bronchitis, secondary bacterial infection of acute bronchitis, community-acquired pneumonia, pharyngitis/tonsilitis, and uncomplicated skin and skin structure infections.
• Substances that inhibit the growth or reproduction of BACTERIA.
• J - Antiinfectives for systemic use
• J01 - Antibacterials for systemic use
• J01F - Macrolides, lincosamides and streptogramins
• QJ - Antiinfectives for systemic use

Synonyms

Dirithromycin; 62013-04-1; Dirithromycine; Dynabac; Diritromicina; Dirithromycinum; LY-237216; LY 237216; 1801D76STL; (9S)-9-Deoxo-11-deoxy-9,11-(imino((1R)-2-(2-methoxyethoxy)ethylidene)oxy)erythromycin; NSC-758672; CHEBI:474014; Erythromycin, 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethylidene)oxy)-, (9S(R))-; DTXCID4028882; (9S)-9-Deoxo-11-deoxy-9,11-[imino[(1R)-2-(2-methoxyethoxy)ethylidene]oxy]erythromycin; RefChem:56882

Frequently Asked Questions

What are the CAS number and molecular formula of Dirithromycin?

CAS 62013-04-1; molecular formula C42H78N2O14; molecular weight — g/mol.

What other names is Dirithromycin known by?

Dirithromycin, 62013-04-1, Dirithromycine, Dynabac, Diritromicina, Dirithromycinum.

Is Dirithromycin classified as hazardous?

Hazard statements reported: H317.

What are the key physical properties of Dirithromycin?

LogP: 1.6.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.