盐酸地昔帕明

盐酸地昔帕明（CAS 58-28-6）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

物理形态与操作说明

• >45.4 [ug/mL] (The mean of the results at pH 7.4)
• 162.1 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

这个物质在各数据库里的编号

数据库记载的用途

• Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
• Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
• Drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants (ANTIDEPRESSIVE AGENTS, TRICYCLIC) and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.

它在各数据库里的别名

Desipramine hydrochloride; 58-28-6; Desipramine Hcl; DMI hydrochloride; RMI 9,384A; Desmethylimipramine chloride; Desimipramine, hydrochloride; NSC-114901; Desipramine monohydrochloride; EX 4355; Demethylimipramine hydrochloride; Imipraminedemethyl hydrochloride; G-35020; Desmethylimipramine hydrochloride; JB-8181; Desmethylimipramine monohydrochloride

计算机算出的分子描述符

数据库摘要

desipramine hydrochloride · CAS 58-28-6 · C18H23ClN2. UNII 1Y58DO4MY1.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。