des-gly10,(D-his(bzl)6)-lh-rh*乙酰胺

Name: des-gly10,(D-his(bzl)6)-lh-rh*乙酰胺
Brand: 济南圣和化工有限公司

CAS 76712-82-8C66H86N18O12MW 1323.5

des-gly10,(D-his(bzl)6)-lh-rh*乙酰胺，CAS 登记号 76712-82-8，由济南圣和化工有限公司现货供应，可提供纯度按批次COA提供(不公开发布) 的规格，下游主要用于医药中间体及原料药。支持样品与小批量试用，批量价格请联系我们获取，验收以批次 COA 为准。

规格参数

CAS号76712-82-8

分子式C66H86N18O12

分子量1323.5

LogP0.7

纯度按批次COA提供(不公开发布)

包装按订单/批次确认(不公开发布)

应用领域医药中间体及原料药

类别医药中间体及原料药

用途与场景

医药中间体及原料药

包装与供货

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

供货周期现货/按订单安排

文件与支持

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常见问题

在哪里能查到 des-gly10,(D-his(bzl)6)-lh-rh*乙酰胺的 CAS 号？

本页已列出 des-gly10,(D-his(bzl)6)-lh-rh*乙酰胺的 CAS 号：76712-82-8，可与随货 COA 核对。

可以提供哪些规格和包装？

常见纯度为按批次COA提供(不公开发布)，包装形式为按订单/批次确认(不公开发布)，特殊规格可在询价时说明。

des-gly10,(D-his(bzl)6)-lh-rh*乙酰胺一般用在什么产品里？

主要涉及医药中间体及原料药。

下单流程是怎样的？

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PubChem 公开数据

Description

des-gly10,(D-his(bzl)6)-lh-rh*ethylamide · CAS 76712-82-8 · C66H86N18O12. UNII H50H3S3W74. Solubility: 10.

Identification

CAS Registry Number	76712-82-8
PubChem CID	25077993
Molecular formula	C66H86N18O12
UNII (FDA)	H50H3S3W74

Computed Descriptors

Molecular Weight	1323.5
XLogP3	0.7
Hydrogen Bond Donor Count	15
Hydrogen Bond Acceptor Count	15
Rotatable Bond Count	34
Exact Mass	1322.66726025
Monoisotopic Mass	1322.66726025
Topological Polar Surface Area	449
Heavy Atom Count	96
Formal Charge	0

Physical & Chemical Properties

Solubility	10

Physical description & handling notes

Specific optical rotation = -33.9 deg at 20 °C/D ( c = 1 in acetic acid)
5.3 (His-base)
Histrelin acetate formulations: Parenteral implants, 50 mg histrelin acetate, Vanta by Valera.

GHS Hazard Classification

Reported hazard statements	H360 (100%)

H360 (100%): May damage fertility or the unborn child [Danger Reproductive toxicity]

P203, P280, P318, P405, and P501 (click each P-code to see the statement)

Documented Uses

Palliative treatment of advanced prostate cancer
Treatment of children with central precocious puberty
THERAP CAT: Treatment of central precocious puberty
J.E.F. Rivier, W.W. Vale Jr., EP 21620; eidem, US 4244946 (both 1981 to Salk Institute)
Synthetic nonapeptide agonist analog of LH-RH.
As the product Supprelin LA (FDA), histrelin is indicated for the treatment of children with central precocious puberty (CPP). As the product Vantas (FDA), histrelin is indicated for the palliative treatment of advanced prostate cancer.

Synonyms

histrelin; 76712-82-8; Histrelina; Histreline; Histrelinum; ORF 17070; RWJ 17070; ORF-17070; H50H3S3W74; RWJ-17070; ((ImBl)-D-His(sub 6),Pro(sub 9)-NEt)LHRH; ORF 17070RWJ 17070; CHEBI:5739; DTXSID50227543; IBHPE-LHRH; RefChem:56340

Frequently Asked Questions

What are the CAS number and molecular formula of des-gly10,(D-his(bzl)6)-lh-rh*ethylamide?

CAS 76712-82-8; molecular formula C66H86N18O12; molecular weight — g/mol.

What other names is des-gly10,(D-his(bzl)6)-lh-rh*ethylamide known by?

histrelin, 76712-82-8, Histrelina, Histreline, Histrelinum, ORF 17070.

Is des-gly10,(D-his(bzl)6)-lh-rh*ethylamide classified as hazardous?

Hazard statements reported: H360.

What are the key physical properties of des-gly10,(D-his(bzl)6)-lh-rh*ethylamide?

Solubility: 10.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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