恩替卡韦

恩替卡韦（CAS 142217-69-4）的公开数据库记录，列此仅供独立核对。

物理形态与操作说明

• Solid
• White to off white powder
• Slightly soluble (2.4 mg/mL at pH 7.9, 25 °C)
• In water, 2.4X10+3 mg/L, temp not specified
• pH = 7.9 in a saturated solution of water at 25 °C
• White to off-white powder, mp: >220 °C. Specific optical rotation: +35 deg at 25 °C/D (c = 0.38 in water). 溶解度 in water: 2.4 mg/mL. pH of saturated solution in water is 7.9 at 25 °C /Entecavir monohydrate/

公开数据库收录的理化数据

这个物质在各数据库里的编号

数据库记载的用途

• Preparation: R. Zahler, W. A. Slusarchyk, European Patent Office 481754; eidem, United States of America patent 5206244 (1992, 1993 both to Squibb)
• For the treatment of chronic hepatitis B virus infection in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.
• Entecavir is a guanosine nucleoside analogue used in the treatment of chronic hepatitis B virus (HBV) infection. Entecavir therapy can be associated with flares of the underlying hepatitis B during or after therapy, but has not been linked to cases of clinically apparent liver injury.
• Breast Feeding; Lactation; Antiviral Agents
• Medicines for hepatitis B > Nucleoside/Nucleotide reverse transcriptase inhibitors
• (1) Oral - Liquid: 0.05 mg per mL; (2) Oral - Solid: 0.5 mg; 1 mg

它在各数据库里的别名

Entecavir; 142217-69-4; Baraclude; anhydrous entecavir; Entecavir anhydrous; BMS 200475; BMS-200475; entecavir (anhydrous); DTXSID4046446; NNU2O4609D; CHEBI:473990; DTXCID2026446; SQ-34676; 2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-6,9-dihydro-3H-purin-6-one; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-

计算机算出的分子描述符

数据库摘要

entecavir · CAS 142217-69-4 · C12H15N5O3. UNII NNU2O4609D. 溶解度: 6.59e+00 g/L; LogP: -0.8.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。