乙胺丁醇二盐酸盐

Description

ethambutol dihydrochloride · CAS 1070-11-7 · C10H26Cl2N2O2. UNII JNG307DJ5X.

Identification

CAS Registry Number	1070-11-7
PubChem CID	14051
Molecular formula	C10H26Cl2N2O2
IUPAC name	(2S)-2-[2-[[(2S)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol;dihydrochloride
UNII (FDA)	JNG307DJ5X

Computed Descriptors

Molecular Weight	277.23
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	9
Exact Mass	276.1371335
Monoisotopic Mass	276.1371335
Topological Polar Surface Area	64.5
Heavy Atom Count	16
Formal Charge	0
Complexity	109

Physical description & handling notes

• 147 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H360 (95.6%)

Documented Uses

• Breast Feeding; Lactation; Milk, Human; Anti-infective Agents; Antitubercular Agents
• Ethambutol hydrochloride is an antibacterial prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of active tuberculosis (TB). (Active TB is also called TB disease.)
• TB can be an opportunistic infection (OI) of HIV.
• Drugs used in the treatment of tuberculosis. They are divided into two main classes: first-line agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and second-line drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy.

Synonyms

Ethambutol dihydrochloride; Ethambutol Hydrochloride; Ethambutol HCL; 1070-11-7; Myambutol; Dadibutol; Dexambutol; Ebutol; Etapiam; Servambutol; Mycobutol; Tambutol; Etibi; CL 40881; DTXSID4045345; QE4VW5FO07

Frequently Asked Questions

What are the CAS number and molecular formula of ethambutol dihydrochloride?

CAS 1070-11-7; molecular formula C10H26Cl2N2O2; molecular weight — g/mol.

What other names is ethambutol dihydrochloride known by?

Ethambutol dihydrochloride, Ethambutol Hydrochloride, Ethambutol HCL, 1070-11-7, Myambutol, Dadibutol.

Is ethambutol dihydrochloride classified as hazardous?

Hazard statements reported: H360.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.