盐酸艾司洛尔

盐酸艾司洛尔（CAS 81161-17-3）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

物理形态与操作说明

• White or off-white crystalline powder
• Crystals from methanol-ether
• Esmolol hydrochloride concentrate for injection should be stored at 15-30 °C. /Esmolol hydrochloride/
• Esmolol hydrochloride concentrate for injection ... /should not be exposed/ to temperatures of 40 °C or higher. /Esmolol hydrochloride/
• At a concentration of 10 mg/ml, esmolol hydrochloride is chemically and physically stable for at least 24 hours at 15-30 °C or when refrigerated in the following IV solutions; 5% dextrose; 5% dextrose and Ringer's or lactated Ringer's, 5% dextrose and 0.45 or 0.9% sodium chloride; lactated Ringer's; or 0.45 or 0.9% sodium; or 5% dextrose and potassium chloride 40 mEq/l.
• In alcohol, 350 mg/l at room temperature

公开数据库收录的理化数据

这个物质在各数据库里的编号

数据库记载的用途

• Esmolol is used IV principally to provide rapid, temporary control of ventricular rate in patients with supraventricular tachyarrhythmias (SVT) (eg, atrial flutter and/or fibrillation, sinus tachycardia).
• Esmolol may be preferred to longer-acting B-adrenergic blocking agents for the short-term control of ventricular rate in patients with SVT because of the drug's rapid onset and short duration of effects, ... .
• For more Therapeutic Uses (Complete) data for ESMOLOL HYDROCHLORIDE (6 total), please visit the HSDB record page.
• ... Esmolol is contraindicated in patients with second- or third-degree atrioventricular blocks, sinus bradycardia, cardiogenic shock, or overt cardiac failure.
• Esmolol may mask signs and symptoms of hypoglycemia (eg, tachycardia, palpitation, blood pressure changes, tremor, feelings of anxiety, but not sweating or dizziness) and may potentiate insulin-induced hypoglycemia; therefore, the drug should be used with caution in patients with diabetes mellitus or hypoglycemia.
• Because of de-esterified metabolite (ASL 8123) of esmolol is eliminated mainly by the kidneys, ... the drug should be used with caution in patients with renal impairment, especially severe impairment.

它在各数据库里的别名

Esmolol hydrochloride; 81161-17-3; Esmolol HCL; Brevibloc; ASL-8052; Asl 8052; DTXSID7049003; Brevibloc in plastic container; V05260LC8D; DTXCID8028929; Brevibloc Double Strength in plastic container; (+-)-Methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate hydrochloride; 4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoic acid methyl ester HCl; Benzenepropanoic acid, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, methyl ester, hydrochloride; CHEBI:4857; RefChem:56564

计算机算出的分子描述符

数据库摘要

Esmolol hydrochloride · CAS 81161-17-3 · C16H26ClNO4. UNII V05260LC8D. 熔点: 85-86 °C; Dissociation Constants: pKa = 9.5.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。