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Home › Product Catalog › Donepezil Hydrochloride

Donepezil Hydrochloride

CAS 120011-70-3C24H30ClNO3MW 416.0

Donepezil Hydrochloride (CAS No. 120011-70-3) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number120011-70-3
Molecular FormulaC24H30ClNO3
Molecular Weight416.0
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Donepezil Hydrochloride?

The CAS number of Donepezil Hydrochloride is 120011-70-3.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Donepezil Hydrochloride?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Donepezil Hydrochloride or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Donepezil Hydrochloride · CAS 120011-70-3 · C24H30ClNO3. UNII 3O2T2PJ89D.

Identification

CAS Registry Number120011-70-3
PubChem CID5741
Molecular formulaC24H30ClNO3
IUPAC name2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;hydrochloride
UNII (FDA)3O2T2PJ89D

Computed Descriptors

Molecular Weight416.0
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass415.1914215
Monoisotopic Mass415.1914215
Topological Polar Surface Area38.8
Heavy Atom Count29
Formal Charge0
Complexity510

Physical description & handling notes

  • 196.6 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statementsH300 (17.9%), H301 (76.2%), H319 (79.8%)

H300 (17.9%): Fatal if swallowed [Danger Acute toxicity, oral]

H301 (76.2%): Toxic if swallowed [Danger Acute toxicity, oral]

Documented Uses

  • For the palliative treatment of mild to moderate dementia of the Alzheimer's type.
  • Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms.
  • Cholinesterase Inhibitors [MoA]; Cholinesterase Inhibitor [EPC]
  • Donepezil is metabolized by CYP 450 isoenzymes 2D6 and 3A4 in the liver and also undergoes glucuronidation. The main metabolite, 6-O-desmethyl donepezil, has been reported to inhibit AChE to the same extent as donepezil in vitro. Route of Elimination: Donepezil is both excreted in the urine intact and extensively metabolized to four major metabolites, two of which are known to be active, and a number of minor metabolites, not all of which have been identified. Half Life: 70 hours

Synonyms

Donepezil hydrochloride; 120011-70-3; Donepezil HCl; BNAG; Aricept ODT; E-2020; E2020; ADLARITY; DTXSID0046698; Aricept Evess; NSC-737535; NSC-758882; 3O2T2PJ89D; DTXCID8026698; 1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hcl; NAMZARIC COMPONENT DONEPEZIL HYDROCHLORIDE

Frequently Asked Questions

What are the CAS number and molecular formula of Donepezil Hydrochloride?

CAS 120011-70-3; molecular formula C24H30ClNO3; molecular weight — g/mol.

What other names is Donepezil Hydrochloride known by?

Donepezil hydrochloride, 120011-70-3, Donepezil HCl, BNAG, Aricept ODT, E-2020.

Is Donepezil Hydrochloride classified as hazardous?

Hazard statements reported: H300, H301, H319.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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Supplier: Jinan Shenghe Chemical Co., Ltd. · Reply within one business day.

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