格列本脲

Name: 格列本脲
Brand: 济南圣和化工有限公司

CAS 10238-21-8C23H28ClN3O5SMW 494.0

格列本脲，CAS 登记号 10238-21-8，由济南圣和化工有限公司现货供应，可提供纯度按批次COA提供(不公开发布) 的规格，下游主要用于医药中间体及原料药。支持样品与小批量试用，批量价格请联系我们获取，验收以批次 COA 为准。

规格参数

CAS号10238-21-8

分子式C23H28ClN3O5S

分子量494.0

熔点169

LogP3.754

纯度按批次COA提供(不公开发布)

包装按订单/批次确认(不公开发布)

应用领域医药中间体及原料药

类别医药中间体及原料药

用途与场景

医药中间体及原料药

包装与供货

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

供货周期现货/按订单安排

文件与支持

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本页已列出格列本脲的 CAS 号：10238-21-8，可与随货 COA 核对。

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主要涉及医药中间体及原料药。

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PubChem 公开数据

Description

Glybenzcyclamide · CAS 10238-21-8 · C23H28ClN3O5S. UNII SX6K58TVWC. Melting Point: 169; Melting Point: 169 - 170 °C; Solubility: 2.06e-03 g/L.

Identification

CAS Registry Number	10238-21-8
PubChem CID	3488
Molecular formula	C23H28ClN3O5S
IUPAC name	5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
UNII (FDA)	SX6K58TVWC

Computed Descriptors

Molecular Weight	494.0
XLogP3	4.8
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	8
Exact Mass	493.1438199
Monoisotopic Mass	493.1438199
Topological Polar Surface Area	122
Heavy Atom Count	33
Formal Charge	0

Physical & Chemical Properties

Melting Point	169
Melting Point	169 - 170 °C
Solubility	2.06e-03 g/L
LogP	3.754
LogP	4.7
LogP	3.09

Physical description & handling notes

Solid
213.2 Å² [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID0037237]
206.6 Å² [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID0037237]
217.6 Å² [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID0037237]
204.7 Å² [M+H]+ [CCS Type: TW; Method: Major Mix IMS/Tof Calibration Kit (Waters)]
205.4 Å² [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Regulatory Status

GHS notification summary	1.1% (1 / 95)

GHS Hazard Classification

GHS notification summary	1.1% (1 / 95)
Reported hazard statements	H302 (89.5%), H413 (93.7%)

This chemical does not meet GHS hazard criteria for 1.1% (1 of 95) of reports.

H302 (89.5%): Harmful if swallowed [Warning Acute toxicity, oral]

Documented Uses

Use (kg; approx.) in Germany (2009): >750
Use (kg) in France (2004): 1092
Consumption (g per capita; approx.) in Germany (2009): 0.00916
Consumption (g per capita) in the USA (2002): 0.0127
Consumption (g per capita) in France (2004): 0.0181
Glyburide is indicated alone or as part of combination product with metformin, as an adjunct to diet and exercise, to improve glycemic control in adults with type 2 diabetes mellitus.

Synonyms

Glibenclamide; glyburide; 10238-21-8; Glynase; Euglucon; Semi-daonil; Libanil; Calabren; Lederglib; Glibenclamida; Glibenclamidum; Glyburide (micronized); HB 419; 1-(p-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea; 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide; Gliken

Frequently Asked Questions

What are the CAS number and molecular formula of Glybenzcyclamide?

CAS 10238-21-8; molecular formula C23H28ClN3O5S; molecular weight — g/mol.

What other names is Glybenzcyclamide known by?

Glibenclamide, glyburide, 10238-21-8, Glynase, Euglucon, Semi-daonil.

Is Glybenzcyclamide classified as hazardous?

1.1% of GHS notifications report no hazard classification (1 of 95).

What are the key physical properties of Glybenzcyclamide?

Melting Point: 169; Melting Point: 169 - 170 °C; Solubility: 2.06e-03 g/L; LogP: 3.754.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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