盐酸依替福林

Description

Etilefrine HCl · CAS 709-55-7 · C10H15NO2. UNII ZB6F8MY53V. Melting Point: 208-209.

Identification

CAS Registry Number	709-55-7
PubChem CID	3306
Molecular formula	C10H15NO2
IUPAC name	3-[2-(ethylamino)-1-hydroxyethyl]phenol
UNII (FDA)	ZB6F8MY53V

Computed Descriptors

Molecular Weight	181.23
XLogP3	0.1
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Exact Mass	181.110278721
Monoisotopic Mass	181.110278721
Topological Polar Surface Area	52.5
Heavy Atom Count	13
Formal Charge	0

Physical & Chemical Properties

Melting Point	208-209

Physical description & handling notes

• 18.9 [ug/mL] (The mean of the results at pH 7.4)

GHS Hazard Classification

Reported hazard statements	H301 (50%), H302 (50%), H312 (50%), H315 (50%), H319 (50%), H332 (50%), H335 (50%), H412 (50%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >100
• Consumption (g per capita; approx.) in Germany (2009): 0.00122
• Drugs that selectively bind to and activate alpha adrenergic receptors.
• Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
• Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
• Drugs used to cause constriction of the blood vessels.

Synonyms

Etilefrine; Etilefrin; 709-55-7; 3-[2-(Ethylamino)-1-hydroxyethyl]phenol; N-Ethylnorphenylephrine; Ethylphenylephrine; Ethyladrianol; Etilefrina; dl-Etilefrin; (+-)-Etilefrine; Ethylefrine; Etilefrinum; Corcanfol; Ethylnorphenylephrine; 1-(3-Hydroxyphenyl)-2-(ethylamino)ethanol; alpha-((Ethylamino)methyl)-m-hydroxybenzyl alcohol

Frequently Asked Questions

What are the CAS number and molecular formula of Etilefrine HCl?

CAS 709-55-7; molecular formula C10H15NO2; molecular weight — g/mol.

What other names is Etilefrine HCl known by?

Etilefrine, Etilefrin, 709-55-7, 3-[2-(Ethylamino)-1-hydroxyethyl]phenol, N-Ethylnorphenylephrine, Ethylphenylephrine.

Is Etilefrine HCl classified as hazardous?

Hazard statements reported: H301, H302, H312, H315, H319.

What are the key physical properties of Etilefrine HCl?

Melting Point: 208-209.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.