盐酸氯丙嗪

Description

Chlorpromazine HCl · CAS 69-09-0 · C17H19ClN2S.ClH. UNII 9WP59609J6.

Identification

CAS Registry Number	69-09-0
PubChem CID	6240
Molecular formula	C17H19ClN2S.ClH
IUPAC name	3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine;hydrochloride
UNII (FDA)	9WP59609J6

Computed Descriptors

Molecular Weight	355.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Exact Mass	354.0724252
Monoisotopic Mass	354.0724252
Topological Polar Surface Area	31.8
Heavy Atom Count	22
Formal Charge	0
Complexity	339

Physical description & handling notes

• Chlorpromazine hydrochloride appears as white or creamy-white odorless crystalline powder with very bitter taste. pH (5% aqueous solution) 4.0-5.5. pH (10% aqueous solution) 4-5. (NTP, 1992)
• 378 to 385 °F (decomposes) (NTP, 1992)
• greater than or equal to 100 mg/mL at 75 °F (NTP, 1992)

GHS Hazard Classification

Reported hazard statements	H301 (99.2%), H330 (94.6%)

Documented Uses

• 10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl-, hydrochloride (1:1): ACTIVE
• Breast Feeding; Lactation; Milk, Human; Antipsychotic Agents; Phenothiazines
• Drugs used to prevent NAUSEA or VOMITING.
• Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
• Phenothiazines [CS]; Phenothiazine [EPC]

Synonyms

Chlorpromazine hydrochloride; 69-09-0; Chlorpromazine Hcl; Sonazine; Chloractil; Klorproman; Klorpromex; Marazine; Norcozine; Promacid; Plegomazin; Promapar; Hebanil; Hibernal; Hybernal; Neurazine

Frequently Asked Questions

What are the CAS number and molecular formula of Chlorpromazine HCl?

CAS 69-09-0; molecular formula C17H19ClN2S.ClH; molecular weight — g/mol.

What other names is Chlorpromazine HCl known by?

Chlorpromazine hydrochloride, 69-09-0, Chlorpromazine Hcl, Sonazine, Chloractil, Klorproman.

Is Chlorpromazine HCl classified as hazardous?

Hazard statements reported: H301, H330.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.