Silver Sulfadiazine

Description

Silver Sulfadiazine · CAS 22199-08-2 · C10H9AgN4O2S. UNII W46JY43EJR. Melting Point: 285.

Identification

CAS Registry Number	22199-08-2
PubChem CID	441244
Molecular formula	C10H9AgN4O2S
IUPAC name	silver (4-aminophenyl)sulfonyl-pyrimidin-2-ylazanide
UNII (FDA)	W46JY43EJR

Computed Descriptors

Molecular Weight	357.14
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Exact Mass	355.94971
Monoisotopic Mass	355.94971
Topological Polar Surface Area	95.3
Heavy Atom Count	18
Formal Charge	0
Complexity	327

Physical & Chemical Properties

Melting Point	285

Physical description & handling notes

• Silver sulfadiazine has broad antimicrobial activity. It is bactericidal for many gram- negative and gram-positive bacteria as well as being effective against yeast. Silver sulfadiazine is not a carbonic anhydrase inhibitor and may be useful in situations where such agents are contraindicated.

Regulatory Status

GHS notification summary	6.4% (3 / 47)

GHS Hazard Classification

GHS notification summary	6.4% (3 / 47)
Reported hazard statements	H315 (93.6%), H319 (91.5%), H335 (91.5%)

Documented Uses

• Indicated as an adjunct for the prevention and treatment of wound sepsis in patients with second- and third-degree burns.
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Dermatological medicines > Anti-infective medicines
• Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.
• Established Pharmacologic Class [EPC] - Sulfonamide Antibacterial
• Chemical Structure [CS] - Sulfonamides

Synonyms

silver sulfadiazine; 22199-08-2; SULFADIAZINE SILVER; Sulfadiazine silver salt; Flamazine; Silver sulphadiazine; Silvadene; Dermazin; Thermazene; Sulfadiazine, silver; Sildaflo; silver sulfadiazinate; SSD AF; Silvazine; Altreet-ag; DTXSID4048646

Frequently Asked Questions

What are the CAS number and molecular formula of Silver Sulfadiazine?

CAS 22199-08-2; molecular formula C10H9AgN4O2S; molecular weight — g/mol.

What other names is Silver Sulfadiazine known by?

silver sulfadiazine, 22199-08-2, SULFADIAZINE SILVER, Sulfadiazine silver salt, Flamazine, Silver sulphadiazine.

Is Silver Sulfadiazine classified as hazardous?

6.4% of GHS notifications report no hazard classification (3 of 47).

What are the key physical properties of Silver Sulfadiazine?

Melting Point: 285.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.