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fluticasone

CAS 90566-53-3C22H27F3O4SMW 444.5

fluticasone (CAS No. 90566-53-3) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Organic Chemicals. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number90566-53-3
Molecular FormulaC22H27F3O4S
Molecular Weight444.5
LogP3.2
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsOrganic Chemicals
CategoryOrganic Chemicals

Where it is used

Organic Chemicals

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of fluticasone?

The CAS number of fluticasone is 90566-53-3.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of fluticasone?

Main applications include Organic Chemicals.

How do I buy fluticasone or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

fluticasone · CAS 90566-53-3 · C22H27F3O4S. UNII CUT2W21N7U.

Identification

CAS Registry Number90566-53-3
PubChem CID5311101
Molecular formulaC22H27F3O4S
IUPAC nameS-(fluoromethyl) (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carbothioate
UNII (FDA)CUT2W21N7U

Computed Descriptors

Molecular Weight444.5
XLogP33.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count3
Exact Mass444.15821500
Monoisotopic Mass444.15821500
Topological Polar Surface Area99.9
Heavy Atom Count30
Formal Charge0

Physical description & handling notes

  • Crystals. MW 500.57. MP 272-273 °C (decomposes). Specific optical rotation: +30 deg at 25 °C/D (c = 0.35). Practically insolluble in water. Freely soluble in dimethylsulfoxide, dimethyl formate; slightly soluble in methanol, 95% ethanol. /Fluticasone propionate/
  • Systemically, in vitro experiments show [DB08906] activates glucocorticoid receptors, inhibits nuclear factor kappa b, and inhibits lung eosinophilia in rats. [DB00588] performs similar activity but is not stated to affect nuclear factor kappa b. [DB00588] as a topical formulation is also associated with vasoconstriction in the skin.
  • Each gram of fluticasone propionate cream contains fluticasone propionate 0.5 mg in a base of propylene glycol, mineral oil, cetostearyl alcohol, Ceteth-20, isopropyl myristate, dibasic sodium phosphate, citric acid, purified water, and imidurea as preservative. /Fluticasone propionate/
  • Each gram of fluticasone propionate ointment contains fluticasone propionate 0.05 mg in a base of liquid paraffin, microcrystalline wax, propylene glycol, and sorbitan sesquioleate. /Fluticasone propionate/
  • Fluticasone propionate HFA inhalation aerosols (44, 110, 220 ug) are pressurized metered-dose aerosol units fitted with a counter. ... Each unit contains a microcrystalline suspension of fluticasone propionate (micronized) in propellant HFA-134a (1,1,1,2-tetrafluoroethane). It contains no other excipients. /Fluticasone propionate/

GHS Hazard Classification

Reported hazard statementsH302 (100%), H312 (100%), H315 (100%), H319 (100%), H332 (100%)

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]

Documented Uses

  • Relieve inflammatory and pruritic symptoms of dermatoses and psoriases, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the treatment of asthma /Fluticasone propionate/
  • Fluticasone propionate is claimed to exert a topical effect on the lungs without significant systemic effects, due to its low systemic bioavailability. /Fluticasone propionate/
  • THERAP CAT: Antiallergic; antiasthmatic; anti-inflammatory /Fluticasone propionate/
  • Use (kg; approx.) in Germany (2009): >75
  • Consumption (g per capita; approx.) in Germany (2009): 0.000916
  • 6alpha,9-difluoro-11beta-hydroxy-16alpha-methyl-3-oxo-17-propanoyloxy)androsta-1,4-diene-17beta-carboxylic acid

Synonyms

fluticasone; 90566-53-3; Fluticasona; Fluticasonum; Fluticaps; Optinose; CUT2W21N7U; Opn-375; CHEBI:5134; DTXSID0044022; HFA, Flovent; Propionate, Fluticasone; RefChem:55221; DTXCID60820064; Flunase; Fluticaps (TN)

Frequently Asked Questions

What are the CAS number and molecular formula of fluticasone?

CAS 90566-53-3; molecular formula C22H27F3O4S; molecular weight — g/mol.

What other names is fluticasone known by?

fluticasone, 90566-53-3, Fluticasona, Fluticasonum, Fluticaps, Optinose.

Is fluticasone classified as hazardous?

Hazard statements reported: H302, H312, H315, H319, H332.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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