乙磺酸丙氯拉嗪 USP

Description

prochlorperazine edisylate usp · CAS 1257-78-9 · C22H30ClN3O6S3. UNII PG20W5VQZS.

Identification

CAS Registry Number	1257-78-9
PubChem CID	91499
Molecular formula	C22H30ClN3O6S3
IUPAC name	2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid
UNII (FDA)	PG20W5VQZS

Computed Descriptors

Molecular Weight	564.1
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	7
Exact Mass	563.0985269
Monoisotopic Mass	563.0985269
Topological Polar Surface Area	161
Heavy Atom Count	35
Formal Charge	0
Complexity	668

Physical description & handling notes

• 73.3 [ug/mL] (The mean of the results at pH 7.4)
• 182.9 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H302 (100%)

Documented Uses

• For the symptomatic management of psychotic disorders, short term management of nonpsychotic anxiety in patients with generalized anxiety disorder, and for the control of severe nausea and vomiting of various causes.
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Drugs used to prevent NAUSEA or VOMITING.
• Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
• Phenothiazines [CS]; Phenothiazine [EPC]
• Hepatic. Undergoes metabolism in the gastric mucosa and on first pass through the liver, CYP2D6 and/or CYP3A4. Half Life: 6 to 8 hours

Synonyms

Prochlorperazine edisylate; 1257-78-9; prochlorperazine ethanedisulfonate; Prochlorperazine Edisylate Salt; PG20W5VQZS; NSC-757299; Prochlorperazine edisilate; DTXSID4074483; Prochlorperazine edisylate (USP); Prochlorperazine edisylate [USP]; 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine edisylate; NSC665801; 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine 1,2-ethanedisulfonate (1:1); Phenothiazine, 2-chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-, ethanedisulfonate; 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine 1,2-ethanedisulfonate (1:1); RefChem:55922

Frequently Asked Questions

What are the CAS number and molecular formula of prochlorperazine edisylate usp?

CAS 1257-78-9; molecular formula C22H30ClN3O6S3; molecular weight — g/mol.

What other names is prochlorperazine edisylate usp known by?

Prochlorperazine edisylate, 1257-78-9, prochlorperazine ethanedisulfonate, Prochlorperazine Edisylate Salt, PG20W5VQZS, NSC-757299.

Is prochlorperazine edisylate usp classified as hazardous?

Hazard statements reported: H302.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.