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Polyethylene Glycol 400

CAS 107-21-1C2H6O2MW 62.07

Polyethylene Glycol 400 (CAS 107-21-1) — formula C2H6O2, molecular weight 62.07; category pharmaceutical intermediates and APIs.

Specifications

CAS Number107-21-1
Molecular FormulaC2H6O2
Molecular Weight62.07
Melting Point9 °F (NTP, 1992)
Boiling Point387.7 °F at 760 mmHg (NTP, 1992)
LogP-1.4
CategoryPharma Excipients

Purchase Profile

What this product is

Polyethylene Glycol 400 is a pharmaceutical intermediate or API compound with CAS registry number 107-21-1 and molecular formula C2H6O2 (molecular weight 62.07), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.

Identification

CAS number: 107-21-1

Its molecular formula C2H6O2 comprises 2 C, 6 H, 2 O atoms.

Also known as: Polyethylene Glycol 400 · Ethylene glycol · PEG 1000 · Polyethylene glycol 200

Category: pharmaceutical intermediates and APIs

Frequently Asked Questions

What is the CAS number of Polyethylene Glycol 400?

The CAS registry number of Polyethylene Glycol 400 is 107-21-1.

What is the molecular formula and molecular weight of Polyethylene Glycol 400?

Molecular formula C2H6O2, molecular weight 62.07.

What other names is Polyethylene Glycol 400 known by?

It is also registered under: Polyethylene Glycol 400, Ethylene glycol, PEG 1000, Polyethylene glycol 200.

Which category does Polyethylene Glycol 400 belong to?

Category: Pharma Excipients.

PubChem Public Data

Public-database records for Polyethylene Glycol 400 (CAS 107-21-1), reproduced here for independent cross-checking.

Safety classification and hazard statements

GHS notification summary0.1% (3 / 8196)
Reported hazard statementsH302, H373 (24.8%), H315, H320, H332, H335, H336, H370

H302: Harmful if swallowed [Warning Acute toxicity, oral]

P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)

Regulatory listings

Regulatory & Food ContactFDA Cumulative Estimated Daily Intake (CEDI): FCS
FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS
ADJUVANT; CARRIER_SOLVENT: Food Additives
Addition polymers of ethylene oxide and water usually designated by a number roughly corresponding to the mole
MACROGOL
JECFA ADI: 0-10 mg/kg bw
GHS notification summary0.1% (3 / 8196)

Physical description and handling notes

  • Ethylene glycol is a clear, colorless syrupy liquid. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. Since it is a liquid it can easily penetrate the soil and contaminate groundwater and nearby streams.
  • CBI; Other Solid; Liquid
  • PEG 400 is a clear, viscous, colourless or almost colourless hygroscopic liquid; PEG 3000, PEG 3350, PEG 4000, PEG 6000 and PEG 8000 are white or almost white solids with a waxy or paraffin-like appearance
  • Clear, colorless, syrupy, odorless liquid. [antifreeze] [Note: A solid below 9 degrees F.]; [NIOSH]
  • Liquid
  • ODOURLESS COLOURLESS VISCOUS HYGROSCOPIC LIQUID.

Reported physical properties

沸点387.7 °F at 760 mmHg (NTP, 1992)
沸点197.3 °C
沸点197.00 to 198.00 °C. @ 760.00 mm Hg
沸点197 °C
沸点388 °F
沸点197.3 °C @760 [mm Hg]
熔点9 °F (NTP, 1992)
熔点-12.69 °C
熔点4 - 10 °C
熔点-13 °C

How this substance is indexed

CAS Registry Number107-21-1
PubChem CID174
分子式C2H6O2
IUPAC 名称ethane-1,2-diol
UNII(FDA)FC72KVT52F

Documented uses

  • CIR ingredient: Ethylene Glycol
  • Ethylene glycol is used as antifreeze in cooling and heating systems, in hydraulic brake fluids, as an industrial humectant, as an ingredient of electrolytic condensers, as a solvent in the paint and plastics industries, in the formulations of printers' inks, stamp pad inks, and inks for ballpoint pens, as a softening agent for cellophane, and in the synthesis of safety explosives, plasticizers, synthetic fibers (Terylene, Dacron), and synthetic waxes.
  • Used in antifreeze and deicing solutions for cars, boats, and aircraft; also used as a solvent for paints, plastics, photographic developing solutions, coolants, hydraulic fluids, and inks; [ATSDR ToxFAQs] Highest risk for exposure in deicing aircraft and runways; [Reference #2] Occupational exposure mainly through skin and eyes, but also inhalation if heated or aerosolized; 50% solution used to de-ice bridges; Has been used in adhesives, polishes, cosmetics, and pharmaceuticals; [ACGIH]
  • Painting (Solvents) [Category: Paint]
  • Working with Glues and Adhesives [Category: Other]
  • Photographic Processing [Category: Other]

Names this substance appears under

ETHYLENE GLYCOL; Ethane-1,2-diol; 107-21-1; 1,2-ethanediol; glycol; monoethylene glycol; 2-hydroxyethanol; 1,2-Dihydroxyethane; Glycol alcohol; Ethylene alcohol; Fridex; Tescol; Norkool; Ethylene dihydrate; Zerex; ethanediol

Computed molecular descriptors

分子量62.07
XLogP3-1.4
氢键供体数2
氢键受体数2
可旋转键数1
精确质量62.036779430
单同位素质量62.036779430
拓扑极性表面积40.5
重原子数4
形式电荷0

Database abstract

Polyethylene glycol 200 · CAS 107-21-1 · C2H6O2. UNII FC72KVT52F. 沸点: 387.7 °F at 760 mmHg (NTP, 1992); 沸点: 197.3 °C; 沸点: 197.00 to 198.00 °C. @ 760.00 mm Hg.

Source: PubChem / Wikidata; the batch COA governs where values differ.

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