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Fosphenytoin

CAS 93390-81-9C16H15N2O6PMW 362.27

Fosphenytoin(CAS 93390-81-9):分子式 C16H15N2O6P、分子量 362.27。

规格参数

CAS号93390-81-9
分子式C16H15N2O6P
分子量362.27
熔点173-176.5 °C
LogP0.6

采购档案

这个产品是什么

Fosphenytoin 是一种化工化合物,登记 CAS 号为 93390-81-9,分子式 C16H15N2O6P(分子量 362.27)。

识别信息

登记 CAS 号:93390-81-9

其分子式 C16H15N2O6P 由 16 个碳、15 个氢、2 个氮、6 个氧、1 个磷 组成。

别名/同义词:Fosphenytoin · Caffeine citrate

常见问题

Fosphenytoin 的 CAS 号是多少?

Fosphenytoin 的 CAS 登记号为 93390-81-9。

Fosphenytoin 的分子式与分子量是多少?

分子式 C16H15N2O6P,分子量 362.27。

Fosphenytoin 还有哪些别名?

别名/同义词:Fosphenytoin、Caffeine citrate。

PubChem 公开数据

Fosphenytoin(CAS 93390-81-9)的公开数据库记录,列此仅供独立核对。

物理形态与操作说明

  • Solid
  • White crystals from acetone
  • Mol wt: 406.24. White crystals as the dihydrate from water-ethanol-acetone, mp 220 °C (softens). pH of a saturated aqueous solution: approx 9. 溶解度 at 25 °C (mg/mL): 142 in water /Disodium salt/
  • Cerebyx

公开数据库收录的理化数据

熔点173-176.5 °C
溶解度1.45e-01 g/L

这个物质在各数据库里的编号

CAS Registry Number93390-81-9
PubChem CID56339
分子式C16H15N2O6P
IUPAC 名称(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)methyl dihydrogen phosphate
UNII(FDA)B4SF212641

数据库记载的用途

  • Consumption (g per capita) in the USA (2002): 0.000986
  • For the control of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery. It can also be substituted, short-term, for oral phenytoin.
  • Prepn: V.J. Stella, K.B. Sloan, US 4260769 (1981 to INTERx).
  • Marketing status: None (Tentative approval) /Sodium/
  • Fosphenytoin is indicated for the treatment of generalized tonic-clonic status epilepticus and for the prevention and treatment of seizures occurring during neurosurgery in adult patients. It can also be substituted, short-term, for oral phenytoin in patients aged two years and older when oral phenytoin administration is not possible.
  • Fosphenytoin is a water-soluble prodrug formulation of phenytoin. It received FDA approval in 1996 for use in epilepsy. It is most commonly used in acute scenarios as an anti-epileptic drug (AED) and a substitute for phenytoin when there are contraindications to phenytoin. Initially, its use was as a short-term oral substitute for oral phenytoin. However, it quickly gained acceptance as a prophylactic drug for patients undergoing neurosurgery.

它在各数据库里的别名

Fosphenytoin; 93390-81-9; Fosfenitoina; Fosphenytoine; (3-Phosphoryloxymethyl)phenytoin; Fosphenytoinum; DTXSID9044299; NP-06; [(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)methoxy]phosphonic acid; B4SF212641; ACC-9653; DTXCID7024299; 2,4-Imidazolidinedione, 5,5-diphenyl-3-((phosphonooxy)methyl)-; 2,4-Imidazolidinedione, 5,5-diphenyl-3-((phosphonooxy)methyl)-, (SP-4-2)-; HMPDP; 3-(hydroxymethyl)phenytoin phosphate ester

计算机算出的分子描述符

分子量362.27
XLogP30.6
氢键供体数3
氢键受体数6
可旋转键数5
精确质量362.06677320
单同位素质量362.06677320
拓扑极性表面积116
重原子数25
形式电荷0

数据库摘要

Fosphenytoin · CAS 93390-81-9 · C16H15N2O6P. UNII B4SF212641. 熔点: 173-176.5 °C; 溶解度: 1.45e-01 g/L.

数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。

获取 Fosphenytoin 报价

供应商:济南圣和化工有限公司 · 一个工作日内回复。

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