Insulin

CAS 9004-10-8C256H381N65O77S6MW 5794

Insulin（CAS 9004-10-8）：分子式 C256H381N65O77S6、分子量 5794；类别有机化学品。

规格参数

CAS号9004-10-8

分子式C256H381N65O77S6

分子量5794

LogP-12.8

应用领域Uses: Hormone of carbohydrate and lipid metabolism that is used to treat diabetes、[Merck Index]、MEDICATION、Indicated as an adjunct to diet and exercise to improve glycemic control in adults and children with type 1 and type 2 diabetes mellitus.、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Methods of Manufacturing: EXTRACTION OF THE PANCREAS OF SLAUGHTERED ANIMALS WITH ACIDIFIED DILUTE ALCOHOL、FOLLOWED BY PRECIPITATION WITH ABSOLUTE ALCOHOL、REDISSOLUTION、PRECIPITATION WITH ZINC CHLORIDE、& REDISSOLUTION IN WATER、SYNTHESIS OF HUMAN INSULIN: KATSOYAMIS ET AL、J AM CHEM SOC 88、164、166 (1966)、RUTTENBERG、SCIENCE 177、623 (1972) (FROM PORCINE INSULIN). ... APPROACHES TO COMMERCIAL SYNTHESIS: CHEM & ENG NEWS 52、19 (APRIL 29、1974).、BY USE OF PORCINE INSULIN AS STARTING MATERIAL、HUMAN INSULIN CAN NOW BE SYNTHESIZED WITH RELATIVE EASE.、Formulations、Preparations: ISOPHANE INSULIN SUSPENSION、USP (NPH INSULIN、ISOPHANE INSULIN)、GLOBIN ZINC INSULIN INJECTION、USP、PROTAMINE ZINC INSULIN SUSPENSION、INSULIN、INSULIN ZINC SUSPENSION PROMPT、INSULIN ZINC SUSPENSION (AMORPHOUS)、SEMILENTE ILETIN & INSULIN ZINC SUSPENDED EXTENDED、INSULIN ZINC SUSPENSION (CRYSTALLINE)、ULTRALENTE ILETIN、INSULIN ZINC SUSPENSION、Consumption Patterns: ESSENTIALLY 100% AS A MEDICINAL (1976)、U.S. Production: (1972) PROBABLY GREATER THAN 4.54X10+5 G、(1975) PROBABLY GREATER THAN 4.54X10+5 G、U.S. Imports: (1972) No Data、(1975) No Data、U.S. Exports: (1972) No Data、General Manufacturing Information: SINCE MOST SYNTHETIC METHODS GIVE LOW YIELDS、MAJOR SOURCE OF HORMONE FOR HUMAN CONSUMPTION REMAINS PANCREAS OF SLAUGHTERED ANIMALS.、INSULIN CAN EXIST AS MONOMER、DIMER、OR HEXAMER COMPOSED OF THREE SUCH DIMERS.、ON CONVERSION OF HUMAN PROINSULIN TO INSULIN、4 BASIC AMINO ACIDS (ARGININE 31、32、LYSINE 64 & ARGININE 65) & CONNECTOR OR C-PEPTIDE MADE UP OF RESIDUES 31-65 ARE REMOVED. RESULTANT INSULIN MOLECULE...A CHAIN WITH GLYCINE AS AMINO-TERMINAL RESIDUE & B CHAIN WITH PHENYLALANINE @ AMINO TERMINUS.、WITH MOL WT OF ABOUT 6000、IS MADE UP OF TWO CHAINS OF AMINO ACIDS JOINED TOGETHER BY DISULFIDE LINKAGES. ...THE TWO CHAINS、ARE、TERMED A FOR ACIDIC & B FOR BASIC...、For more General Manufacturing Information (Complete) data for INSULIN INJECTION (7 total)、please visit the HSDB record page.

类别Organic Chemicals

用途与场景

登记用途：Uses: Hormone of carbohydrate and lipid metabolism that is used to treat diabetes、[Merck Index]、MEDICATION、Indicated as an adjunct to diet and exercise to improve glycemic control in adults and children with type 1 and type 2 diabetes mellitus.、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Methods of Manufacturing: EXTRACTION OF THE PANCREAS OF SLAUGHTERED ANIMALS WITH ACIDIFIED DILUTE ALCOHOL、FOLLOWED BY PRECIPITATION WITH ABSOLUTE ALCOHOL、REDISSOLUTION、PRECIPITATION WITH ZINC CHLORIDE、& REDISSOLUTION IN WATER、SYNTHESIS OF HUMAN INSULIN: KATSOYAMIS ET AL、J AM CHEM SOC 88、164、166 (1966)、RUTTENBERG、SCIENCE 177、623 (1972) (FROM PORCINE INSULIN). ... APPROACHES TO COMMERCIAL SYNTHESIS: CHEM & ENG NEWS 52、19 (APRIL 29、1974).、BY USE OF PORCINE INSULIN AS STARTING MATERIAL、HUMAN INSULIN CAN NOW BE SYNTHESIZED WITH RELATIVE EASE.、Formulations、Preparations: ISOPHANE INSULIN SUSPENSION、USP (NPH INSULIN、ISOPHANE INSULIN)、GLOBIN ZINC INSULIN INJECTION、USP、PROTAMINE ZINC INSULIN SUSPENSION、INSULIN、INSULIN ZINC SUSPENSION PROMPT、INSULIN ZINC SUSPENSION (AMORPHOUS)、SEMILENTE ILETIN & INSULIN ZINC SUSPENDED EXTENDED、INSULIN ZINC SUSPENSION (CRYSTALLINE)、ULTRALENTE ILETIN、INSULIN ZINC SUSPENSION、Consumption Patterns: ESSENTIALLY 100% AS A MEDICINAL (1976)、U.S. Production: (1972) PROBABLY GREATER THAN 4.54X10+5 G、(1975) PROBABLY GREATER THAN 4.54X10+5 G、U.S. Imports: (1972) No Data、(1975) No Data、U.S. Exports: (1972) No Data、General Manufacturing Information: SINCE MOST SYNTHETIC METHODS GIVE LOW YIELDS、MAJOR SOURCE OF HORMONE FOR HUMAN CONSUMPTION REMAINS PANCREAS OF SLAUGHTERED ANIMALS.、INSULIN CAN EXIST AS MONOMER、DIMER、OR HEXAMER COMPOSED OF THREE SUCH DIMERS.、ON CONVERSION OF HUMAN PROINSULIN TO INSULIN、4 BASIC AMINO ACIDS (ARGININE 31、32、LYSINE 64 & ARGININE 65) & CONNECTOR OR C-PEPTIDE MADE UP OF RESIDUES 31-65 ARE REMOVED. RESULTANT INSULIN MOLECULE...A CHAIN WITH GLYCINE AS AMINO-TERMINAL RESIDUE & B CHAIN WITH PHENYLALANINE @ AMINO TERMINUS.、WITH MOL WT OF ABOUT 6000、IS MADE UP OF TWO CHAINS OF AMINO ACIDS JOINED TOGETHER BY DISULFIDE LINKAGES. ...THE TWO CHAINS、ARE、TERMED A FOR ACIDIC & B FOR BASIC...、For more General Manufacturing Information (Complete) data for INSULIN INJECTION (7 total)、please visit the HSDB record page.。

采购档案

这个产品是什么

Insulin 是一种以碳骨架为基础的有机化合物，登记 CAS 号为 9004-10-8，分子式 C256H381N65O77S6（分子量 5794），归属于有机化学品大类化工原料。

识别信息

登记 CAS 号：9004-10-8

其分子式 C256H381N65O77S6 由 256 个碳、381 个氢、65 个氮、77 个氧、6 个硫组成。

别名/同义词：Insulin · Bovine Insulin

所属分类：有机化学品

常见问题

Insulin 的 CAS 号是多少？

Insulin 的 CAS 登记号为 9004-10-8。

Insulin 的分子式与分子量是多少？

分子式 C256H381N65O77S6，分子量 5794。

Insulin 还有哪些别名？

别名/同义词：Insulin、Bovine Insulin。

Insulin 的登记用途是什么？

登记用途：Uses: Hormone of carbohydrate and lipid metabolism that is used to treat diabetes、[Merck Index]、MEDICATION、Indicated as an adjunct to diet and exercise to improve glycemic control in adults and children with type 1 and type 2 diabetes mellitus.、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Methods of Manufacturing: EXTRACTION OF THE PANCREAS OF SLAUGHTERED ANIMALS WITH ACIDIFIED DILUTE ALCOHOL、FOLLOWED BY PRECIPITATION WITH ABSOLUTE ALCOHOL、REDISSOLUTION、PRECIPITATION WITH ZINC CHLORIDE、& REDISSOLUTION IN WATER、SYNTHESIS OF HUMAN INSULIN: KATSOYAMIS ET AL、J AM CHEM SOC 88、164、166 (1966)、RUTTENBERG、SCIENCE 177、623 (1972) (FROM PORCINE INSULIN). ... APPROACHES TO COMMERCIAL SYNTHESIS: CHEM & ENG NEWS 52、19 (APRIL 29、1974).、BY USE OF PORCINE INSULIN AS STARTING MATERIAL、HUMAN INSULIN CAN NOW BE SYNTHESIZED WITH RELATIVE EASE.、Formulations、Preparations: ISOPHANE INSULIN SUSPENSION、USP (NPH INSULIN、ISOPHANE INSULIN)、GLOBIN ZINC INSULIN INJECTION、USP、PROTAMINE ZINC INSULIN SUSPENSION、INSULIN、INSULIN ZINC SUSPENSION PROMPT、INSULIN ZINC SUSPENSION (AMORPHOUS)、SEMILENTE ILETIN & INSULIN ZINC SUSPENDED EXTENDED、INSULIN ZINC SUSPENSION (CRYSTALLINE)、ULTRALENTE ILETIN、INSULIN ZINC SUSPENSION、Consumption Patterns: ESSENTIALLY 100% AS A MEDICINAL (1976)、U.S. Production: (1972) PROBABLY GREATER THAN 4.54X10+5 G、(1975) PROBABLY GREATER THAN 4.54X10+5 G、U.S. Imports: (1972) No Data、(1975) No Data、U.S. Exports: (1972) No Data、General Manufacturing Information: SINCE MOST SYNTHETIC METHODS GIVE LOW YIELDS、MAJOR SOURCE OF HORMONE FOR HUMAN CONSUMPTION REMAINS PANCREAS OF SLAUGHTERED ANIMALS.、INSULIN CAN EXIST AS MONOMER、DIMER、OR HEXAMER COMPOSED OF THREE SUCH DIMERS.、ON CONVERSION OF HUMAN PROINSULIN TO INSULIN、4 BASIC AMINO ACIDS (ARGININE 31、32、LYSINE 64 & ARGININE 65) & CONNECTOR OR C-PEPTIDE MADE UP OF RESIDUES 31-65 ARE REMOVED. RESULTANT INSULIN MOLECULE...A CHAIN WITH GLYCINE AS AMINO-TERMINAL RESIDUE & B CHAIN WITH PHENYLALANINE @ AMINO TERMINUS.、WITH MOL WT OF ABOUT 6000、IS MADE UP OF TWO CHAINS OF AMINO ACIDS JOINED TOGETHER BY DISULFIDE LINKAGES. ...THE TWO CHAINS、ARE、TERMED A FOR ACIDIC & B FOR BASIC...、For more General Manufacturing Information (Complete) data for INSULIN INJECTION (7 total)、please visit the HSDB record page.。

Insulin 属于哪个分类？

所属分类：Organic Chemicals。

PubChem 公开数据

Insulin（CAS 9004-10-8）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

GHS notification summary	99.1% (116 / 117)

This chemical does not meet GHS hazard criteria for 99.1% (116 of 117) of all reports.

Reported as not meeting GHS hazard criteria by 116 of 117 companies (only 0.9% companies provided GHS information). For more detailed information, please visit ECHA C&L website.

法规与备案状态

GHS notification summary	99.1% (116 / 117)

物理形态与操作说明

Solid; [Merck Index]
COLORLESS OR ALMOST COLORLESS IF CONTAINING NOT MORE THAN 100 USP UNITS/ML; STRAW-COLORED IF CONTAINING 500 UNITS
CRYSTALS HEXAGONAL SYSTEM, USUALLY OBTAINED AS FLAT RHOMBOHEDRA & CONTAINING 0.4% ZINC
READILY SOL IN DILUTE ACIDS; SOL IN WATER
READILY SOL IN ALKALIES; PRACTICALLY INSOL FROM PH 4.5-7.0; CRYSTALS CONTAINING 2% ZN @ PH 7 ARE MUCH LESS SOL
SHOULD BE STORED AT 2 TO 8 °C & SHOULD NOT BE SUBJECTED TO FREEZING OR EXTREMES IN TEMP

公开数据库收录的理化数据

pH	2.5-3.5

这个物质在各数据库里的编号

CAS Registry Number	9004-10-8
PubChem CID	70678557
分子式	C256H381N65O77S6

数据库记载的用途

Hormone of carbohydrate and lipid metabolism that is used to treat diabetes; [Merck Index]
Indicated as an adjunct to diet and exercise to improve glycemic control in adults and children with type 1 and type 2 diabetes mellitus.
Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
EXTRACTION OF THE PANCREAS OF SLAUGHTERED ANIMALS WITH ACIDIFIED DILUTE ALCOHOL, FOLLOWED BY PRECIPITATION WITH ABSOLUTE ALCOHOL, REDISSOLUTION, PRECIPITATION WITH ZINC CHLORIDE, & REDISSOLUTION IN WATER
SYNTHESIS OF HUMAN INSULIN: KATSOYAMIS ET AL, J AM CHEM SOC 88, 164, 166 (1966); RUTTENBERG, SCIENCE 177, 623 (1972) (FROM PORCINE INSULIN). ... APPROACHES TO COMMERCIAL SYNTHESIS: CHEM & ENG NEWS 52, 19 (APRIL 29, 1974).
BY USE OF PORCINE INSULIN AS STARTING MATERIAL, HUMAN INSULIN CAN NOW BE SYNTHESIZED WITH RELATIVE EASE.

它在各数据库里的别名

9004-10-8; Endopancrine; Decurvon; Dermulin; Insular; Insulyl; Iszilin; Musulin; Iletin; Intesulin B; Insulina dalanatada; Insulinum dalanatum; AERx; INSULIN INJECTION; Insulina iniettabile neutra; Insulini injectio neutralis

计算机算出的分子描述符

分子量	5794
XLogP3	-12.8
氢键供体数	78
氢键受体数	89
可旋转键数	178
精确质量	5791.6287098
单同位素质量	5789.6220002
拓扑极性表面积	2450
重原子数	404
形式电荷	0

数据库摘要

Insulin · CAS 9004-10-8 · C256H381N65O77S6. pH: 2.5-3.5.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。