多索茶碱

Description

Doxofylline · CAS 69975-86-6 · C11H14N4O4. UNII MPM23GMO7Z.

Identification

CAS Registry Number	69975-86-6
PubChem CID	50942
Molecular formula	C11H14N4O4
IUPAC name	7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione
UNII (FDA)	MPM23GMO7Z

Computed Descriptors

Molecular Weight	266.25
XLogP3	-0.9
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	266.10150494
Monoisotopic Mass	266.10150494
Topological Polar Surface Area	76.9
Heavy Atom Count	19
Formal Charge	0

Physical description & handling notes

• Insoluble
• >39.9 [ug/mL] (The mean of the results at pH 7.4)

GHS Hazard Classification

Reported hazard statements	H302 (100%), H315 (33.3%), H319 (33.3%)

Documented Uses

• Indicated for the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and pulmonary disease with spastic bronchial component.
• Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally.
• Agents that cause an increase in the expansion of a bronchus or bronchial tubes.
• Compounds which inhibit or antagonize the biosynthesis or actions of phosphodiesterases.
• R03 - Drugs for obstructive airway diseases
• R03D - Other systemic drugs for obstructive airway diseases

Synonyms

DOXOFYLLINE; 69975-86-6; Doxophylline; Dioxyfilline; Ansimar; Ventax; Doxofilina; Doxofyllinum; Synasma; ABC 12/3; 7-(1,3-Dioxolan-2-ylmethyl)theophylline; DTXSID7022968; ABC-12/3; MPM23GMO7Z; NSC-759645; CHEBI:94714

Frequently Asked Questions

What are the CAS number and molecular formula of Doxofylline?

CAS 69975-86-6; molecular formula C11H14N4O4; molecular weight — g/mol.

What other names is Doxofylline known by?

DOXOFYLLINE, 69975-86-6, Doxophylline, Dioxyfilline, Ansimar, Ventax.

Is Doxofylline classified as hazardous?

Hazard statements reported: H302, H315, H319.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.