右哌甲酯

Description

Dexmethylphenidate · CAS 40431-64-9 · C14H19NO2. UNII M32RH9MFGP. Melting Point: >203.

Identification

CAS Registry Number	40431-64-9
PubChem CID	154101
Molecular formula	C14H19NO2
IUPAC name	methyl (2R)-2-phenyl-2-[(2R)-piperidin-2-yl]acetate
UNII (FDA)	M32RH9MFGP

Computed Descriptors

Molecular Weight	233.31
XLogP3	0.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Exact Mass	233.141578849
Monoisotopic Mass	233.141578849
Topological Polar Surface Area	38.3
Heavy Atom Count	17
Formal Charge	0

Physical & Chemical Properties

Melting Point	>203

Physical description & handling notes

• Solid
• Dexmethylphenidate is the d-enantiomer of methylphenidate. This enantiomer is more pharmacologically active than the racemic mixture and may block norepinephrine and dopamine reuptake in synapses.

Documented Uses

• Dexmethylphenidate is used as a treatment for ADHD, ideally in conjunction with psychological, educational, behavioral or other forms of treatment.
• Breast Feeding; Lactation; Milk, Human; Adrenergic Agents; Central Nervous System Stimulants; Dopamine Agents; Sympathomimetics; Wakefulness-Promoting Agents
• Dexmethylphenidate (Class: Piperidines/PEA, Added Date: 08-2006)
• Dexmethylphenidate/Serdexmethylphenidate (Class: Depressants and Tranquilizers, Added Date: 01-2024)
• Avoid alcohol. Alcohol inhibits the metabolism of dexmethylphenidate.
• A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here.

Synonyms

Dexmethylphenidate; d-threo-Methylphenidate; (+)-threo-Methylphenidate; 40431-64-9; dexmetilfenidato; Attenade; D-TMP; M32RH9MFGP; dexmethylphenidatum; methyl (2R)-2-phenyl-2-[(2R)-piperidin-2-yl]acetate; CHEBI:51860; methyl (R)-phenyl[(R)-piperidin-2-yl]acetate; DTXSID70893769; methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate; 2-Piperidineacetic acid, alpha-phenyl-, methyl ester, (alphaR,2R)-; METHYL (2R)-PHENYL((2R)-PIPERIDIN-2-YL)ACETATE

Frequently Asked Questions

What are the CAS number and molecular formula of Dexmethylphenidate?

CAS 40431-64-9; molecular formula C14H19NO2; molecular weight — g/mol.

What other names is Dexmethylphenidate known by?

Dexmethylphenidate, d-threo-Methylphenidate, (+)-threo-Methylphenidate, 40431-64-9, dexmetilfenidato, Attenade.

What are the key physical properties of Dexmethylphenidate?

Melting Point: >203.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.