七叶苷水合物

七叶苷水合物（CAS 531-75-9）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

法规与备案状态

物理形态与操作说明

• Solid
• 174 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 193.73 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 182.53 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 164.77 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 172.99 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

公开数据库收录的理化数据

这个物质在各数据库里的编号

数据库记载的用途

• 2H-1-Benzopyran-2-one, 6-(.beta.-D-glucopyranosyloxy)-7-hydroxy-: ACTIVE
• As medication, esculin is sometimes used as a vasoprotective agent. Esculin is also used in a microbiology laboratory to aid in the identification of bacterial species (especially Enterococci and Listeria), as all strains of Group D Streptococci hydrolyze æsculin in 40% bile.
• Rarely, absorbed into the blood stream if used as a combination with other ingredients in suppository form. But, Applying cream or ointment form to open wound or skin may lead this drug to absorb and circulate into blood stream.
• After oral administration of esculin (100 mg/kg) for rats, plasma, urine, feces and bile samples were collected to screen metabolites. As a result, a total of 19 metabolites (10 phase I metabolites and 9 phase II metabolites) were found and identified. It was also found that after oral administration of esculin, the esculin could be metabolized to esculetin in vivo via deglycosylation, and esculetin was found in all biological samples.
• Absorption half life about 1 hour and elimination half life about 20 hours
• The main activities of Esculine focus on capillary protection, as it improves capillary permeability and fragility. It is reported to inhibit catabolic enzymes such as hyaluronidase and collagenase, thus preserving the integrity of the perivascular connective tissue. Esculine also showed good antioxidant properties, protecting triglycerides against auto-oxidation at high temperatures . The antioxidant property might as well explain some of the anti-inflammatory activity of the product, making it a suitable product

它在各数据库里的别名

Esculin; 531-75-9; Esculetin 6-O-glucoside; 6,7-Dihydroxycoumarin 6-glucoside; Esculetin 6-beta-D-glucoside; 6,7-Dihydroxycoumarin-6-O-glucoside; 7-Hydroxy-6-cumarinyl-glucosid; DTXSID7045318; 6-(beta-D-Glucopyranosyloxy)-7-hydroxy-cumarin; 1Y1L18LQAF; CHEBI:4853; DTXCID5025318; NSC-26665; 7-hydroxy-2-oxo-2H-chromen-6-yl beta-D-glucopyranoside; 7-hydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one; 2H-1-Benzopyran-2-one, 6-(beta-D-glucopyranosyloxy)-7-hydroxy-

计算机算出的分子描述符

数据库摘要

Esculin hydrate · CAS 531-75-9 · C15H16O9. UNII 1Y1L18LQAF. 熔点: 205 °C.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。