大豆异黄酮

大豆异黄酮（CAS 574-12-9）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

法规与备案状态

这个物质在各数据库里的编号

数据库记载的用途

• Indicated for over-the-counter use as a dietary supplement for increasing bone density and regulating blood fat.
• Renal excretion is the predominant route of elimination for dietary isoflavones, where approximately 10-60% of total administered dose is excreted in urine. Glucuronide conjugates account for the majority (70-90%) of the isoflavone content in urine, followed by sulphate conjugates (10-25%) and aglycone forms (1-10%). Fecal excretion is minimal, which accounts for 1-4% of the dietary isoflavone ingested.
• Isoflavones are readily distributed to all tissues, and they are known to cross the placental barrier and blood brain barrier. They are also distributed to the extra-vascular compartments. In a human study, the volume of distribution of daidzein and genistein were 336.25 L and 258.76 L, respectively.
• In a human study, the clearance rate for daidzein and genistein were 30.09 L/h and 21.85 L/h, respectively.
• No pharmacokinetic data available.
• The half-life of isoflavones is between 4 and 8 h. Daidzein has a longer intestinal half-life than genistein due to more rapid degradation of genistein. Individual half-life of daidzein and genistein in a human pharmacokinetic study were 7.75 h and 7.77 h, respectively.

它在各数据库里的别名

Isoflavone; 574-12-9; 3-Phenylchromone; 3-phenyl-4H-1-benzopyran-4-one; isoflavon; OVO2KUW8H8; NSC-135405; NSC135405; DTXSID90205986; CHEBI:18220; Homoisoflavone; Isoflavones; Isoflavone Derivative; Derivative, Isoflavone; 3 Benzylchroman 4 One; 3 Benzylchroman 4 Ones

计算机算出的分子描述符

数据库摘要

SOYBEAN ISOFLAVONE · CAS 574-12-9 · C15H10O2. UNII OVO2KUW8H8.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。