盐酸阿米替林

盐酸阿米替林（CAS 549-18-8）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

法规与备案状态

物理形态与操作说明

• >47.1 [ug/mL] (The mean of the results at pH 7.4)
• 166.3 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

这个物质在各数据库里的编号

数据库记载的用途

• For the treatment of depression, chronic pain, irritable bowel syndrome, sleep disorders, diabetic neuropathy, agitation and insomnia, and migraine prophylaxis.
• 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride (1:1): INACTIVE
• Amitriptyline Hydrochloride; Chlordiazepoxide
• Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
• A subclass of analgesic agents that typically do not bind to OPIOID RECEPTORS and are not addictive. Many non-narcotic analgesics are offered as NONPRESCRIPTION DRUGS.
• Drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants (ANTIDEPRESSIVE AGENTS, TRICYCLIC) and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.

它在各数据库里的别名

Amitriptyline hydrochloride; 549-18-8; Amitriptyline HCl; Syneudon; Etravil; Novoprotect; Amitid; Amitril; Saroten Retard; NIH 10794; DTXSID9033187; 26LUD4JO9K; NSC-104210; Amitriptylini hydrochloridum; 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride; DTXCID7013187

计算机算出的分子描述符

数据库摘要

AMITRIPTYLINE HCl · CAS 549-18-8 · C20H24ClN. UNII 26LUD4JO9K.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。