氟替卡松

氟替卡松（CAS 90566-53-3）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

物理形态与操作说明

• Crystals. MW 500.57. MP 272-273 °C (decomposes). Specific optical rotation: +30 deg at 25 °C/D (c = 0.35). Practically insolluble in water. Freely soluble in dimethylsulfoxide, dimethyl formate; slightly soluble in methanol, 95% ethanol. /Fluticasone propionate/
• Systemically, in vitro experiments show [DB08906] activates glucocorticoid receptors, inhibits nuclear factor kappa b, and inhibits lung eosinophilia in rats. [DB00588] performs similar activity but is not stated to affect nuclear factor kappa b. [DB00588] as a topical formulation is also associated with vasoconstriction in the skin.
• Each gram of fluticasone propionate cream contains fluticasone propionate 0.5 mg in a base of propylene glycol, mineral oil, cetostearyl alcohol, Ceteth-20, isopropyl myristate, dibasic sodium phosphate, citric acid, purified water, and imidurea as preservative. /Fluticasone propionate/
• Each gram of fluticasone propionate ointment contains fluticasone propionate 0.05 mg in a base of liquid paraffin, microcrystalline wax, propylene glycol, and sorbitan sesquioleate. /Fluticasone propionate/
• Fluticasone propionate HFA inhalation aerosols (44, 110, 220 ug) are pressurized metered-dose aerosol units fitted with a counter. ... Each unit contains a microcrystalline suspension of fluticasone propionate (micronized) in propellant HFA-134a (1,1,1,2-tetrafluoroethane). It contains no other excipients. /Fluticasone propionate/

这个物质在各数据库里的编号

数据库记载的用途

• Relieve inflammatory and pruritic symptoms of dermatoses and psoriases, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the treatment of asthma /Fluticasone propionate/
• Fluticasone propionate is claimed to exert a topical effect on the lungs without significant systemic effects, due to its low systemic bioavailability. /Fluticasone propionate/
• THERAP CAT: Antiallergic; antiasthmatic; anti-inflammatory /Fluticasone propionate/
• Use (kg; approx.) in Germany (2009): >75
• Consumption (g per capita; approx.) in Germany (2009): 0.000916
• 6alpha,9-difluoro-11beta-hydroxy-16alpha-methyl-3-oxo-17-propanoyloxy)androsta-1,4-diene-17beta-carboxylic acid

它在各数据库里的别名

fluticasone; 90566-53-3; Fluticasona; Fluticasonum; Fluticaps; Optinose; CUT2W21N7U; Opn-375; CHEBI:5134; DTXSID0044022; HFA, Flovent; Propionate, Fluticasone; RefChem:55221; DTXCID60820064; Flunase; Fluticaps (TN)

计算机算出的分子描述符

数据库摘要

fluticasone · CAS 90566-53-3 · C22H27F3O4S. UNII CUT2W21N7U.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。