福沙那韦钙

Description

Fosamprenavir calcium · CAS 226700-81-8 · C25H34CaN3O9PS. UNII ID1GU2627N.

Identification

CAS Registry Number	226700-81-8
PubChem CID	131535
Molecular formula	C25H34CaN3O9PS
IUPAC name	calcium [(2R,3S)-1-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-[[(3S)-oxolan-3-yl]oxycarbonylamino]-4-phenylbutan-2-yl] phosphate
UNII (FDA)	ID1GU2627N

Computed Descriptors

Molecular Weight	623.7
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	13
Exact Mass	623.1379287
Monoisotopic Mass	623.1379287
Topological Polar Surface Area	192
Heavy Atom Count	40
Formal Charge	0
Complexity	901

GHS Hazard Classification

Reported hazard statements	H315 (33.3%), H351 (66.7%), H361 (66.7%), H362 (33.3%), H373 (33.3%)

Documented Uses

• Breast Feeding; Lactation; Milk, Human; Anti-Infective Agents; Antiviral Agents; Anti-HIV Agents; Anti-Retroviral Agents; HIV Protease Inhibitors
• Fosamprenavir is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV in adults and children. Fosamprenavir is always used in combination with other HIV medicines.
• Although fosamprenavir is FDA-approved for use in adults and children, it is no longer commonly used or recommended as an HIV treatment. The Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents With HIV and the Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection no longer contain detailed or updated information on the use of fosamprenavir. Please refer to the FDA drug label for additional information regarding the use of fosamprenavir in people with HIV.
• HIV medicines cannot cure HIV/AIDS, but using HIV medicines as directed by a health care provider helps people with HIV live longer, healthier lives. HIV medicines also reduce the risk of HIV transmission. If you are using HIV medicines, do not cut down on, skip, or stop using them unless your health care provider tells you to.
• Lexiva (brand products discontinued)
• Inhibitors of HIV PROTEASE, an enzyme required for production of proteins needed for viral assembly.

Synonyms

Fosamprenavir calcium; 226700-81-8; Fosamprenavir Calcium Salt; Lexiva; Telzir; GW 433908G; DTXSID0046777; GW433908G; GW-433908G; ID1GU2627N; DTXCID8026777; RefChem:55231; Fosamprenavir (Calcium Salt); Fosamprenavir calcium [USAN]; CAS-226700-81-8; MFCD08141843

Frequently Asked Questions

What are the CAS number and molecular formula of Fosamprenavir calcium?

CAS 226700-81-8; molecular formula C25H34CaN3O9PS; molecular weight — g/mol.

What other names is Fosamprenavir calcium known by?

Fosamprenavir calcium, 226700-81-8, Fosamprenavir Calcium Salt, Lexiva, Telzir, GW 433908G.

Is Fosamprenavir calcium classified as hazardous?

Hazard statements reported: H315, H351, H361, H362, H373.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.