胍乙酸

Description

Guanidineacetic acid · CAS 352-97-6 · C3H7N3O2. UNII GO52O1A04E. Solubility: 3.6 mg/mL at 15 °C; Collision Cross Section: 125.4 Ų [M+H]+; Collision Cross Section: 134.4 Ų [M+Na]+.

Identification

CAS Registry Number	352-97-6
PubChem CID	763
Molecular formula	C3H7N3O2
IUPAC name	2-(diaminomethylideneamino)acetic acid
UNII (FDA)	GO52O1A04E

Computed Descriptors

Molecular Weight	117.11
XLogP3	-1.6
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Exact Mass	117.053826475
Monoisotopic Mass	117.053826475
Topological Polar Surface Area	102
Heavy Atom Count	8
Formal Charge	0

Physical & Chemical Properties

Solubility	3.6 mg/mL at 15 °C
Collision Cross Section	125.4 Ų [M+H]+
Collision Cross Section	134.4 Ų [M+Na]+

Physical description & handling notes

• Solid
• 134.6 Ų [M+Na]+ [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]
• 124.9 Ų [M+H]+ [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]
• 124.8 Ų [M+H]+ [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]
• 126.88 Ų [M+H]+ [CCS Type: DT; Method: stepped-field]

Regulatory Status

GHS notification summary	2.2% (1 / 46)

GHS Hazard Classification

GHS notification summary	2.2% (1 / 46)
Reported hazard statements	H315 (97.8%), H319 (97.8%), H335 (95.7%)

Documented Uses

• Naturally produced by the body (endogenous). Is used as a supplement to enhance athletic performance.
• Analogs of those substrates or compounds which bind naturally at the active sites of proteins, enzymes, antibodies, steroids, or physiological receptors. These analogs form a stable covalent bond at the binding site, thereby acting as inhibitors of the proteins or steroids.
• Guanidino acetic acid (GAA) is synthesized in the liver and kidney from Arg and Gly and subsequently methylated by S-adenosylmethionine to form creatine. The conversion of guaniodacetate to creatinine in the liver causes a depletion of methyl groups. This causes homocysteine levels to rise, which has been shown to produce cardiovascular and skeletal problems.
• 3-Phosphoglycerate dehydrogenase deficiency
• Arginine and proline metabolism
• Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency)

Synonyms

glycocyamine; guanidinoacetic acid; 352-97-6; Guanidineacetic acid; Guanidoacetic acid; N-amidinoglycine; Guanyl glycine; Betacyamine; Betasyamine; guanidinoacetate; Guanidylacetic acid; glycine, N-(aminoiminomethyl)-; GLYCINE, N-AMIDINO-; Guanidine, (carboxymethyl)-; amidinoglycine; 2-(diaminomethylideneamino)acetic acid

Frequently Asked Questions

What are the CAS number and molecular formula of Guanidineacetic acid?

CAS 352-97-6; molecular formula C3H7N3O2; molecular weight — g/mol.

What other names is Guanidineacetic acid known by?

glycocyamine, guanidinoacetic acid, 352-97-6, Guanidineacetic acid, Guanidoacetic acid, N-amidinoglycine.

Is Guanidineacetic acid classified as hazardous?

2.2% of GHS notifications report no hazard classification (1 of 46).

What are the key physical properties of Guanidineacetic acid?

Solubility: 3.6 mg/mL at 15 °C; Collision Cross Section: 125.4 Ų [M+H]+; Collision Cross Section: 134.4 Ų [M+Na]+.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.