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GIMERACIL

CAS 103766-25-2C5H4ClNO2MW 145.54

GIMERACIL (CAS No. 103766-25-2) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Organic Chemicals. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number103766-25-2
Molecular FormulaC5H4ClNO2
Molecular Weight145.54
LogP-0.1
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsOrganic Chemicals
CategoryOrganic Chemicals

Where it is used

Organic Chemicals

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of GIMERACIL?

The CAS number of GIMERACIL is 103766-25-2.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of GIMERACIL?

Main applications include Organic Chemicals.

How do I buy GIMERACIL or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

GIMERACIL · CAS 103766-25-2 · C5H4ClNO2. UNII UA8SE1325T.

Identification

CAS Registry Number103766-25-2
PubChem CID54679224
Molecular formulaC5H4ClNO2
IUPAC name5-chloro-4-hydroxy-1H-pyridin-2-one
UNII (FDA)UA8SE1325T

Computed Descriptors

Molecular Weight145.54
XLogP3-0.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass144.9930561
Monoisotopic Mass144.9930561
Topological Polar Surface Area49.3
Heavy Atom Count9
Formal Charge0

GHS Hazard Classification

Reported hazard statementsH302 (100%), H315 (50%), H319 (50%), H335 (50%)

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]

Documented Uses

  • Gimeracil is used as an adjunct to antineoplastic therapy. When used within the product Teysuno, gimeracil is indicated for the treatment of adults with advanced gastric (stomach) cancer when given in combination with cisplatin.
  • Drink plenty of fluids. Drinking water is important to prevent dehydration when taking Teysuno.
  • Take on an empty stomach. Take Teysuno at least 1 hour before or after eating.
  • Following a single dose of Teysuno, approximately 3.8% to 4.2% of administered tegafur, 65% to 72% of administered gimeracil, and 3.5% to 3.9% of administered oteracil were excreted unchanged in the urine.
  • Although no intravenous data are available for Teysuno in humans, the volume of distribution could be roughly estimated from the apparent volume of distribution and urinary excretion data as 16 l/m2, 17 l/m2, and 23 l/m2 for tegafur, gimeracil and oteracil, respectively.
  • Oteracil, gimeracil, 5-FU, and tegafur are 8.4%, 32.2%, 18.4%, and 52.3% protein bound, respectively.

Synonyms

Gimeracil; 103766-25-2; 5-Chloro-2,4-dihydroxypyridine; gimestat; 5-Chloro-2,4-pyridinediol; DTXSID8046799; Gimeracilo; UA8SE1325T; DTXCID6026799; TEYSUNO COMPONENT GIMERACIL; CDHP; gimeracilum; Chlorodihydroxypyridine; RefChem:639937; 5-chloropyridine-2,4-diol; 5-Chloro-4-hydroxy-1H-pyridin-2-one

Frequently Asked Questions

What are the CAS number and molecular formula of GIMERACIL?

CAS 103766-25-2; molecular formula C5H4ClNO2; molecular weight — g/mol.

What other names is GIMERACIL known by?

Gimeracil, 103766-25-2, 5-Chloro-2,4-dihydroxypyridine, gimestat, 5-Chloro-2,4-pyridinediol, DTXSID8046799.

Is GIMERACIL classified as hazardous?

Hazard statements reported: H302, H315, H319, H335.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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