乙酸胍

乙酸胍（CAS 23256-50-0）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

物理形态与操作说明

• White solid from acetonitrile
• White to almost white powder
• Slight odor
• 溶解度 of 50 mg/ml in alcohol at 25 °C
• Solid; mp: 192.5 °C (decomposition); solubility at 25 °C (mg/ml): propylene glycol 100, chloroform 0.6, ethyl acetate 1 /Guanabenz monoacetate/
• Oral Tablets, 4 mg (of guanabenz), Wytensin, Wyeth; 8 mg (of guanabenz), Wytensin (scored), Wyeth.

公开数据库收录的理化数据

这个物质在各数据库里的编号

数据库记载的用途

• Preparation: J. Yates, E. Haddock, GB 1019120 (1966 to Schell) ... Use as antihypertensive: W. J. Houlihan et al, DE 1804634 (1969 to Sandoz). /Guanabenz/
• Adrenergic alpha-Agonists; Antihypertensive Agents; Sympatholytics
• Guanabenz is used in the management of hypertension. The efficacy of guanabenz in hypertensive patients is similar to that of other adrenergic inhibitors such as clonidine, methyldopa, or beta-adrenergic blocking agents (eg, pindolol, propranolol).
• Guanabenz has been used alone or in combination with naltrexone in the management of opiate withdrawal in patients physically dependent on opiates and undergoing detoxification. Guanabenz has also been used as an analgesic in a limited number of patients with chronic pain; use of the drug permitted a reduction in opiate dosage or discontinuance of opiate therapy in these patients, but additional study is necessary. /Use is not currently included in the labeling approved by the FDA/
• For more Therapeutic Uses (Complete) data for GUANABENZ ACETATE (6 total), please visit the HSDB record page.
• Guanabenz should be used with caution and blood pressure monitored carefully in patients with hepatic and/or renal impairment, since the pharmacokinetics of the drug may be altered in such patients. The drug also should be used with caution in patients with severe coronary insufficiency, recent myocardial infarction, and/or cerebrovascular disease. Guanabenz should also be used with caution in geriatric patients since they may be more sensitive to the hypotensive and sedative effects of the drug.

它在各数据库里的别名

Guanabenz acetate; 23256-50-0; Wytensin; WY-8678 acetate; Guanabenz monoacetate; 443O19GK1A; NSC-757044; Hydrazinecarboximidamide, 2-((2,6-dichlorophenyl)methylene)-, monoacetate; (E)-1-(2,6-Dichlorobenzylideneamino)guanidine monoacetate; 3-((2,6-Dichlorophenyl)methylene)carbazamidine monoacetate; Acetate, Guanabenz; Monoacetate, Guanabenz; RefChem:55289; Guanabenz Acetate Wyeth-Ayerst; Acetate Wyeth-Ayerst, Guanabenz; Wyeth Ayerst of Guanabenz Acetate

计算机算出的分子描述符

数据库摘要

Guanabenz acetate · CAS 23256-50-0 · C10H12Cl2N4O2. UNII 443O19GK1A. 熔点: 227-229 °C (decomposition); 溶解度: In water, 11 mg/ml @ 25 °C; Dissociation Constants: pKa = 8.1.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。