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GSK1120212(DMSO 溶剂化物)

CAS 1187431-43-1C28H29FIN5O5SMW 693.5

GSK1120212(DMSO 溶剂化物),CAS 登记号 1187431-43-1,由济南圣和化工有限公司现货供应,可提供纯度 按批次COA提供(不公开发布) 的规格,下游主要用于有机化学品。支持样品与小批量试用,批量价格请联系我们获取,验收以批次 COA 为准。

规格参数

CAS号1187431-43-1
分子式C28H29FIN5O5S
分子量693.5
纯度按批次COA提供(不公开发布)
包装按订单/批次确认(不公开发布)
应用领域有机化学品
类别有机化学品

用途与场景

有机化学品

包装与供货

包装规格按订单/批次确认(不公开发布)
纯度规格按批次COA提供(不公开发布)
储存条件密封、阴凉干燥处保存
供货周期现货/按订单安排

文件与支持

每批随货提供 COA;可按需提供 MSDS 及技术文件。邮件注明产品名称与 CAS 号,一个工作日内回复报价。

常见问题

在哪里能查到 GSK1120212(DMSO 溶剂化物) 的 CAS 号?

本页已列出 GSK1120212(DMSO 溶剂化物) 的 CAS 号:1187431-43-1,可与随货 COA 核对。

可以提供哪些规格和包装?

常见纯度为 按批次COA提供(不公开发布),包装形式为 按订单/批次确认(不公开发布),特殊规格可在询价时说明。

GSK1120212(DMSO 溶剂化物) 一般用在什么产品里?

主要涉及有机化学品。

下单流程是怎样的?

来信 info@591daili.com 或 WhatsApp 联系,提供产品名称、CAS 号与数量,确认价格与交期后即可安排发货,验收以批次 COA 为准。

PubChem 公开数据

Description

GSK1120212 (DMSO solvate) · CAS 1187431-43-1 · C28H29FIN5O5S. UNII BSB9VJ5TUT.

Identification

CAS Registry Number1187431-43-1
PubChem CID50992434
Molecular formulaC28H29FIN5O5S
IUPAC nameN-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide;methylsulfinylmethane
UNII (FDA)BSB9VJ5TUT

Computed Descriptors

Molecular Weight693.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Exact Mass693.09182
Monoisotopic Mass693.09182
Topological Polar Surface Area138
Heavy Atom Count41
Formal Charge0
Complexity1120

GHS Hazard Classification

Reported hazard statementsH317 (100%), H361 (66.7%), H372 (100%), H400 (33.3%), H410 (100%)

H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]

H361 (66.7%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Documented Uses

  • Mekinist (Trametinib Dimethyl Sulfoxide)
  • Trametinib dimethyl sulfoxide is approved to be used alone or with dabrafenib mesylate to treat patients whose cancer has a certain mutation in the BRAF gene, including:
  • • Anaplastic thyroid cancer that has spread and cannot be treated with local therapy. It is used with dabrafenib mesylate.
  • • Glioma that is low grade in children aged 1 year and older who require systemic therapy. It is used with dabrafenib mesylate.
  • • With dabrafenib mesylate in patients who have had surgery to remove cancer that has spread to the lymph nodes.
  • • Alone or with dabrafenib mesylate in patients whose cancer cannot be removed by surgery or has spread to other parts of the body.

Synonyms

TRAMETINIB DIMETHYL SULFOXIDE; Trametinib DMSO; GSK1120212B; Mekinst; UNII-BSB9VJ5TUT; BSB9VJ5TUT; GSK-1120212B; CHEBI:75991; DTXSID30152223; RefChem:57976; DTXCID0074714; 1187431-43-1; Trametinib DMSO solvate; Trametinib (DMSO solvate); MFCD21609250; Trametinib dimethyl sulfoxide [USAN]

Frequently Asked Questions

What are the CAS number and molecular formula of GSK1120212 (DMSO solvate)?

CAS 1187431-43-1; molecular formula C28H29FIN5O5S; molecular weight — g/mol.

What other names is GSK1120212 (DMSO solvate) known by?

TRAMETINIB DIMETHYL SULFOXIDE, Trametinib DMSO, GSK1120212B, Mekinst, UNII-BSB9VJ5TUT, BSB9VJ5TUT.

Is GSK1120212 (DMSO solvate) classified as hazardous?

Hazard statements reported: H317, H361, H372, H400, H410.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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