己巴比妥

Description

Hexobarbital · CAS 56-29-1 · C12H16N2O3. UNII AL8Z8K3P6S. Melting Point: 146.5; Melting Point: 67.00 °C. @ 760.00 mm Hg; Solubility: 435.

Identification

CAS Registry Number	56-29-1
PubChem CID	3608
Molecular formula	C12H16N2O3
IUPAC name	5-(cyclohexen-1-yl)-1,5-dimethyl-1,3-diazinane-2,4,6-trione
UNII (FDA)	AL8Z8K3P6S

Computed Descriptors

Molecular Weight	236.27
XLogP3	1.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Exact Mass	236.11609238
Monoisotopic Mass	236.11609238
Topological Polar Surface Area	66.5
Heavy Atom Count	17
Formal Charge	0

Physical & Chemical Properties

Melting Point	146.5
Melting Point	67.00 °C. @ 760.00 mm Hg
Solubility	435
Solubility	1.51e+00 g/L
LogP	1.98
LogP	1.71
Dissociation Constants	8.2

Physical description & handling notes

• Solid

GHS Hazard Classification

Reported hazard statements	H302 (100%)

Documented Uses

• For the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful stimuli.
• Hexobarbital (Class: Depressants and Tranquilizers, Added Date: 10-1998)
• Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
• QN05C - Hypnotics and sedatives
• Hexobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABA-A receptor, increasing the duration of time for which the Cl- ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged.

Synonyms

Hexobarbital; Hexobarbitone; Methexenyl; Methylhexabital; 56-29-1; Evipal; Evipan; Sombucaps; Sombulex; Enhexymal; Hexobarbitalum; Hexobarbitonum; 5-(1-CYCLOHEXEN-1-YL)-1,5-DIMETHYLBARBITURIC ACID; Hexobarbital ciii; DTXSID9023122; 5-(1-Cyclohexen-1-yl)-1,5-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione

Frequently Asked Questions

What are the CAS number and molecular formula of Hexobarbital?

CAS 56-29-1; molecular formula C12H16N2O3; molecular weight — g/mol.

What other names is Hexobarbital known by?

Hexobarbital, Hexobarbitone, Methexenyl, Methylhexabital, 56-29-1, Evipal.

Is Hexobarbital classified as hazardous?

Hazard statements reported: H302.

What are the key physical properties of Hexobarbital?

Melting Point: 146.5; Melting Point: 67.00 °C. @ 760.00 mm Hg; Solubility: 435; Solubility: 1.51e+00 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.