盐酸伊立替康三水合物

Description

Irinotecan hydrochloride trihydrate · CAS 136572-09-3 · C33H45ClN4O9. UNII 042LAQ1IIS.

Identification

CAS Registry Number	136572-09-3
PubChem CID	60837
Molecular formula	C33H45ClN4O9
IUPAC name	[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-piperidin-1-ylpiperidine-1-carboxylate;trihydrate;hydrochloride
UNII (FDA)	042LAQ1IIS

Computed Descriptors

Molecular Weight	677.2
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	5
Exact Mass	676.2875067
Monoisotopic Mass	676.2875067
Topological Polar Surface Area	116
Heavy Atom Count	47
Formal Charge	0
Complexity	1200

Documented Uses

• Breast Feeding; Lactation; Milk, Human; Antineoplastic Agents; Enzyme Inhibitors; Topoisomerase I Inhibitors
• Camptosar (Irinotecan Hydrochloride)
• Irinotecan hydrochloride is approved to be used alone or with other drugs to treat:
• • Colorectal cancer that has metastasized (spread to other parts of the body), including metastatic cancer that has recurred (come back) or has not gotten better with other chemotherapy.
• Irinotecan hydrochloride is also being studied in the treatment of other types of cancer. Irinotecan hydrochloride is also available in a different form called irinotecan sucrosofate.
• Compounds that inhibit the activity of DNA TOPOISOMERASE I.

Synonyms

Camptosar; Irinotecan hydrochloride hydrate; CHEBI:90881; RefChem:148744; IRINOTECAN HYDROCHLORIDE Trihydrate; 136572-09-3; Irinotecan Hcl Trihydrate; CPT-11 Trihydrate; MFCD01765731; Irinotecan (hydrochloride trihydrate); (+)-7-Ethyl-10-hydroxycamptothecine 10-(1,4'-bipiperidine)-1'-carboxylate, monohydrochloride, trihydrate; IRINOTECAN HYDROCHLORIDE [ORANGE BOOK]; Irinotecan HCI Trihydrate; UNII-042LAQ1IIS; Camptosar (TN); Onivyde (TN)

Frequently Asked Questions

What are the CAS number and molecular formula of Irinotecan hydrochloride trihydrate?

CAS 136572-09-3; molecular formula C33H45ClN4O9; molecular weight — g/mol.

What other names is Irinotecan hydrochloride trihydrate known by?

Camptosar, Irinotecan hydrochloride hydrate, CHEBI:90881, RefChem:148744, IRINOTECAN HYDROCHLORIDE Trihydrate, 136572-09-3.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.