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Description

Idarubicin · CAS 58957-92-9 · C26H27NO9. UNII ZRP63D75JW. Solubility: 7.72e-01 g/L; LogP: 0.2.

Identification

CAS Registry Number	58957-92-9
PubChem CID	42890
Molecular formula	C26H27NO9
IUPAC name	(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione
UNII (FDA)	ZRP63D75JW

Computed Descriptors

Molecular Weight	497.5
XLogP3	1.9
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	3
Exact Mass	497.16858144
Monoisotopic Mass	497.16858144
Topological Polar Surface Area	177
Heavy Atom Count	36
Formal Charge	0

Physical & Chemical Properties

Solubility	7.72e-01 g/L
LogP	0.2

Physical description & handling notes

• Solid

Documented Uses

• Consumption (g per capita) in the USA (2002): 1.36e-06
• For the treatment of acute myeloid leukemia (AML) in adults. This includes French-American-British (FAB) classifications M1 through M7.
• Breast Feeding; Lactation; Milk, Human; Antineoplastic Agents; Anthracyclines; Antibiotics, Antineoplastic; Topoisomerase II Inhibitors
• Chemical substances, produced by microorganisms, inhibiting or preventing the proliferation of neoplasms.
• Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II.
• Established Pharmacologic Class [EPC] - Anthracycline Topoisomerase Inhibitor

Synonyms

IDARUBICIN; 58957-92-9; 4-Demethoxydaunorubicin; 4-Demethoxydaunomycin; Idarubicina; Idarubicine; Idarubicinum; Zavedos; ZRP63D75JW; NSC 256439; DTXSID7023142; CHEBI:42068; 4-Desmethoxydaunorubicin; 4 Demethoxydaunorubicin; 4 Desmethoxydaunorubicin; RefChem:56926

Frequently Asked Questions

What are the CAS number and molecular formula of Idarubicin?

CAS 58957-92-9; molecular formula C26H27NO9; molecular weight — g/mol.

What other names is Idarubicin known by?

IDARUBICIN, 58957-92-9, 4-Demethoxydaunorubicin, 4-Demethoxydaunomycin, Idarubicina, Idarubicine.

What are the key physical properties of Idarubicin?

Solubility: 7.72e-01 g/L; LogP: 0.2.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.