L-3-(3,4-二羟基苯基)丙氨酸

Description

L-3-(3,4-Dihydroxyphenyl)alanine · CAS 65170-01-6 · C9H11NO4. UNII 46627O600J. Boiling Point: 448.4; Melting Point: 295; Melting Point: 284-286 °C.

Identification

CAS Registry Number	65170-01-6
PubChem CID	6047
Molecular formula	C9H11NO4
IUPAC name	(2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid
UNII (FDA)	46627O600J

Computed Descriptors

Molecular Weight	197.19
XLogP3	-2.7
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	3
Exact Mass	197.06880783
Monoisotopic Mass	197.06880783
Topological Polar Surface Area	104
Heavy Atom Count	14
Formal Charge	0

Physical & Chemical Properties

Boiling Point	448.4
Melting Point	295
Melting Point	284-286 °C
Melting Point	285 °C
Solubility	5mM
Solubility	In water, 5,000 mg/l @ 20 °C
Solubility	5.0 mg/mL
LogP	0.05
LogP	log Kow = -2.39
LogP	-2.39

Physical description & handling notes

• Colorless to white odorless solid; [Merck Index] White crystalline solid; [Sigma-Aldrich MSDS]
• Solid
• Colorless to white crystals or crystalline powder; needles from water
• Odorless
• Tasteless
• Readily sol in dil hydrochloric and formic acids; practically insol in ethanol, benzene, chloroform, ethyl acetate

GHS Hazard Classification

Reported hazard statements	H302 (100%), H315 (32.2%), H319 (52.9%), H335 (30.8%), H361 (30.3%), H372 (14.4%), H411 (26.9%), H412 (15.9%)

Documented Uses

• Natural form of dopa (precursor of the catecholamines); Used to treat Parkinson's disease; [Merck Index]
• Use (kg) in Switzerland (2009): >2500
• Use (kg; approx.) in Germany (2009): >25000
• Use (kg) in France (2004): 24996
• Consumption (g per capita) in Switzerland (2009): 0.32
• Consumption (g per capita; approx.) in Germany (2009): 0.31

Synonyms

levodopa; L-dopa; 59-92-7; 3,4-dihydroxy-L-phenylalanine; Dopar; 3-Hydroxy-L-tyrosine; Larodopa; Bendopa; 3-(3,4-Dihydroxyphenyl)-L-alanine; Levopa; Brocadopa; Dopaidan; Dopalina; Dopasol; Eldopal; Insulamina

Frequently Asked Questions

What are the CAS number and molecular formula of L-3-(3,4-Dihydroxyphenyl)alanine?

CAS 65170-01-6; molecular formula C9H11NO4; molecular weight — g/mol.

What other names is L-3-(3,4-Dihydroxyphenyl)alanine known by?

levodopa, L-dopa, 59-92-7, 3,4-dihydroxy-L-phenylalanine, Dopar, 3-Hydroxy-L-tyrosine.

Is L-3-(3,4-Dihydroxyphenyl)alanine classified as hazardous?

Hazard statements reported: H302, H315, H319, H335, H361.

What are the key physical properties of L-3-(3,4-Dihydroxyphenyl)alanine?

Boiling Point: 448.4; Melting Point: 295; Melting Point: 284-286 °C; Melting Point: 285 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.