盐酸美金刚

Description

Menantine Hydrochloride · CAS 41100-52-1 · C12H22ClN. UNII JY0WD0UA60.

Identification

CAS Registry Number	41100-52-1
PubChem CID	181458
Molecular formula	C12H22ClN
IUPAC name	3,5-dimethyladamantan-1-amine;hydrochloride
UNII (FDA)	JY0WD0UA60

Computed Descriptors

Molecular Weight	215.76
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	215.1440774
Monoisotopic Mass	215.1440774
Topological Polar Surface Area	26
Heavy Atom Count	14
Formal Charge	0
Complexity	240

Physical description & handling notes

• 29.4 [ug/mL] (The mean of the results at pH 7.4)
• 145.1 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Regulatory Status

GHS notification summary	5% (1 / 20)

GHS Hazard Classification

GHS notification summary	5% (1 / 20)
Reported hazard statements	H302 (80%), H312 (15%), H315 (25%), H319 (20%), H332 (15%), H335 (10%), H336 (15%)

Documented Uses

• For the treatment of moderate to severe dementia of the Alzheimer's type.
• Agents used in the treatment of Parkinson's disease. The most commonly used drugs act on the dopaminergic system in the striatum and basal ganglia or are centrally acting muscarinic antagonists.
• Any drugs that are used for their effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons.
• Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists.
• NMDA Receptor Antagonists [MoA]; N-methyl-D-aspartate Receptor Antagonist [EPC]

Synonyms

MEMANTINE HYDROCHLORIDE; 41100-52-1; Memantine HCL; 3,5-dimethyladamantan-1-amine hydrochloride; 3,5-Dimethyl-1-adamantanamine hydrochloride; Akatinol; Namenda XR; Memary; Memantine Mylan; Memantine Merz; Memantine Accord; Memantine LEK; 1-Amino-3,5-dimethyladamantane Hydrochloride; Acrescent; Balaxur; Auxura

Frequently Asked Questions

What are the CAS number and molecular formula of Menantine Hydrochloride?

CAS 41100-52-1; molecular formula C12H22ClN; molecular weight — g/mol.

What other names is Menantine Hydrochloride known by?

MEMANTINE HYDROCHLORIDE, 41100-52-1, Memantine HCL, 3,5-dimethyladamantan-1-amine hydrochloride, 3,5-Dimethyl-1-adamantanamine hydrochloride, Akatinol.

Is Menantine Hydrochloride classified as hazardous?

5% of GHS notifications report no hazard classification (1 of 20).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.