巯基乙酸甲酯

Description

Methyl thioglycolate · CAS 2365-48-2 · C3H6O2S. UNII O1608LA9EL. Boiling Point: 148 °C; Dissociation Constants: pKa= 8.08 @ 25 °C.

Identification

CAS Registry Number	2365-48-2
PubChem CID	16907
Molecular formula	C3H6O2S
IUPAC name	methyl 2-sulfanylacetate
UNII (FDA)	O1608LA9EL

Computed Descriptors

Molecular Weight	106.15
XLogP3	0.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Exact Mass	106.00885060
Monoisotopic Mass	106.00885060
Topological Polar Surface Area	27.3
Heavy Atom Count	6
Formal Charge	0

Physical & Chemical Properties

Boiling Point	148 °C
Dissociation Constants	pKa= 8.08 @ 25 °C

Physical description & handling notes

• Colorless liquid with a stench; [MSDSonline]
• When heated to decomposition it emits toxic fumes of sulfoxides.

Regulatory Status

Regulatory & Food Contact	CIR / INCI: Cosmetic ingredients (Methyl Thioglycolate) -> CIR (Cosmetic Ingredient Review) CIR / INCI: Hair waving or straightening

GHS Hazard Classification

Reported hazard statements	H226 (72.2%), H301 (87.8%), H302 (12.2%), H312 (28.9%), H315 (100%), H317 (27.8%), H319 (100%), H331 (12.2%)

Documented Uses

• CIR ingredient: Methyl Thioglycolate
• Used as chemical intermediate; [HSDB]
• Cosmetics -> Hair waving or straightening
• Acetic acid, 2-mercapto-, methyl ester: ACTIVE
• /Has/ shown promise as raw material in several fine chemicals.
• Can be used as the starting material to obtain methyl 3-amino-2- thiophenecarboxylate ... by reaction with 2-chloroacrylonitrile.

Synonyms

METHYL THIOGLYCOLATE; 2365-48-2; Methyl mercaptoacetate; Methyl 2-mercaptoacetate; Thioglycolic acid methyl ester; Methylthioglycolate; Acetic acid, mercapto-, methyl ester; Methanethiol, methoxy-; Methylmercaptoacetate; USAF EK-7119; Acetic acid, 2-mercapto-, methyl ester; DTXSID0033673; O1608LA9EL; NSC-75117; DTXCID8013673; RefChem:818100

Frequently Asked Questions

What are the CAS number and molecular formula of Methyl thioglycolate?

CAS 2365-48-2; molecular formula C3H6O2S; molecular weight — g/mol.

What other names is Methyl thioglycolate known by?

METHYL THIOGLYCOLATE, 2365-48-2, Methyl mercaptoacetate, Methyl 2-mercaptoacetate, Thioglycolic acid methyl ester, Methylthioglycolate.

What is the regulatory status of Methyl thioglycolate?

Documented regulatory listings: CIR / INCI: Cosmetic ingredients (Methyl Thioglycolate) -> CIR (Cosmetic Ingredient Review); CIR / INCI: Hair waving or straightening.

Is Methyl thioglycolate classified as hazardous?

Hazard statements reported: H226, H301, H302, H312, H315.

What are the key physical properties of Methyl thioglycolate?

Boiling Point: 148 °C; Dissociation Constants: pKa= 8.08 @ 25 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.