莫西普利

Description

Moexipril · CAS 103775-10-6 · C27H34N2O7. UNII WT87C52TJZ. Solubility: 5.85e-03 g/L; LogP: 2.7.

Identification

CAS Registry Number	103775-10-6
PubChem CID	91270
Molecular formula	C27H34N2O7
IUPAC name	(3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
UNII (FDA)	WT87C52TJZ

Computed Descriptors

Molecular Weight	498.6
XLogP3	1.2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	12
Exact Mass	498.23660143
Monoisotopic Mass	498.23660143
Topological Polar Surface Area	114
Heavy Atom Count	36
Formal Charge	0

Physical & Chemical Properties

Solubility	5.85e-03 g/L
LogP	2.7

Physical description & handling notes

• Solid
• Soluble (about 10% weight-to-volume) in distilled water at room temperature as HCl salt.
• Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.

Documented Uses

• Use (kg; approx.) in Germany (2009): >25
• Consumption (g per capita; approx.) in Germany (2009): 0.000305
• For the treatment of hypertension.
• Moexipril is an angiotensin-converting enzyme (ACE) inhibitor which is used in the therapy of hypertension. Moexipril is associated with a low rate of transient serum aminotransferase elevations, but has yet to be linked to instances of acute liver injury.
• Breast Feeding; Lactation; Milk, Human; Antihypertensive Agents; Angiotensin-Converting Enzyme Inhibitors; ACE Inhibitors
• Angiotensin-Converting Enzyme Inhibitors

Synonyms

MOEXIPRIL; 103775-10-6; Moexiprilum; WT87C52TJZ; RS-10085; DTXSID9023330; Moex; RefChem:819096; DTXCID803330; C09AA13; Uniretic; Moexiprilum [INN-Latin]; Moexipril (INN); 109715-88-0; CI-925; CHEMBL1165

Frequently Asked Questions

What are the CAS number and molecular formula of Moexipril?

CAS 103775-10-6; molecular formula C27H34N2O7; molecular weight — g/mol.

What other names is Moexipril known by?

MOEXIPRIL, 103775-10-6, Moexiprilum, WT87C52TJZ, RS-10085, DTXSID9023330.

What are the key physical properties of Moexipril?

Solubility: 5.85e-03 g/L; LogP: 2.7.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.