盐酸米安舍林

Description

mianserin hydrochloride · CAS 21535-47-7 · C18H21ClN2. UNII 2X03TN217S.

Identification

CAS Registry Number	21535-47-7
PubChem CID	68551
Molecular formula	C18H21ClN2
IUPAC name	5-methyl-2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaene;hydrochloride
UNII (FDA)	2X03TN217S

Computed Descriptors

Molecular Weight	300.8
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	0
Exact Mass	300.1393264
Monoisotopic Mass	300.1393264
Topological Polar Surface Area	6.5
Heavy Atom Count	21
Formal Charge	0
Complexity	342

Physical description & handling notes

• >45.1 [ug/mL] (The mean of the results at pH 7.4)

GHS Hazard Classification

Reported hazard statements	H302 (100%), H304 (21.3%), H361 (28.7%), H370 (42.6%)

Documented Uses

• Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
• Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or SEROTONIN RECEPTOR AGONISTS.
• A structurally and mechanistically diverse group of drugs that are not tricyclics or monoamine oxidase inhibitors. The most clinically important appear to act selectively on serotonergic systems, especially by inhibiting serotonin reuptake.

Synonyms

Mianserin hydrochloride; 21535-47-7; Mianserin HCl; Bolvidon; Mianserine hydrochloride; ORG GB 94; Tetramide; 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepine hydrochloride; ORG-GB 94; NSC-759590; DTXSID30944145; 2X03TN217S; CHEBI:31843; Dibenzo(c,f)pyrazino(1,2-a)azepine, 1,2,3,4,10,14b-hexahydro-2-methyl-, monohydrochloride; 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)-pyrazino(1,2-a)azepine monohydrochloride; 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepine hydrochloride

Frequently Asked Questions

What are the CAS number and molecular formula of mianserin hydrochloride?

CAS 21535-47-7; molecular formula C18H21ClN2; molecular weight — g/mol.

What other names is mianserin hydrochloride known by?

Mianserin hydrochloride, 21535-47-7, Mianserin HCl, Bolvidon, Mianserine hydrochloride, ORG GB 94.

Is mianserin hydrochloride classified as hazardous?

Hazard statements reported: H302, H304, H361, H370.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.