甲氯芬那酸

甲氯芬那酸（CAS 644-62-2）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

物理形态与操作说明

• Solid
• 166.71 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 155.91 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 169.79 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 150.51 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• Meclofenamic acid is a nonsteroidal agent which has demonstrated anti-inflammatory, analgesic, and antipyretic activity in laboratory animals.

公开数据库收录的理化数据

这个物质在各数据库里的编号

数据库记载的用途

• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• For the relief of mild to moderate pain, for the treatment of primary dysmenorrhea and for the treatment of idiopathic heavy menstrual blood loss. Also for relief of the signs and symptoms of acute and chronic rheumatoid arthritis and osteoarthritis.
• Breast Feeding; Lactation; Milk, Human; Analgesic Agents; Anti-inflammatory Agents, Nonsteroidal
• Avoid excessive or chronic alcohol consumption. Ingesting alcohol may increase the risk of developing a gastrointestinal bleed.
• Take with or without food. Taking meclofenamic acid with food reduces the rate and extent of its absorption; however it also reduces gastrointestinal upset caused by meclofenamic acid.
• Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.

它在各数据库里的别名

meclofenamic acid; meclofenamate; 644-62-2; Arquel; 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid; Acido meclofenamico; Acide meclofenamique; INF 4668; Acidum meclofenamicum; N-(2,6-Dichloro-m-tolyl)anthranilic acid; CI-583; INF-4668; Meclomen; N-(3-Methyl-2,6-dichlorophenyl)anthranilic acid; 2-((2,6-Dichloro-3-methylphenyl)amino)benzoic acid; N-(2,6-Dichloro-3-methylphenyl)anthranilic acid

计算机算出的分子描述符

数据库摘要

Meclofenamic acid · CAS 644-62-2 · C14H11Cl2NO2. UNII 48I5LU4ZWD. 熔点: 248-250; 熔点: 257 °C; 溶解度: 30.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。