盐酸莫西西利特

Description

moxisylyte hydrochloride · CAS 964-52-3 · C16H25NO3. UNII PW8QYA7KI0. Boiling Point: 371ºC at 760 mmHg; Melting Point: 145ºC; Solubility: >47.4 ug/ml.

Identification

CAS Registry Number	964-52-3
PubChem CID	4260
Molecular formula	C16H25NO3
IUPAC name	[4-[2-(dimethylamino)ethoxy]-2-methyl-5-propan-2-ylphenyl] acetate
UNII (FDA)	PW8QYA7KI0

Computed Descriptors

Molecular Weight	279.37
XLogP3	3.2
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	7
Exact Mass	279.18344366
Monoisotopic Mass	279.18344366
Topological Polar Surface Area	38.8
Heavy Atom Count	20
Formal Charge	0

Physical & Chemical Properties

Boiling Point	371ºC at 760 mmHg
Melting Point	145ºC
Solubility	>47.4 ug/ml
LogP	3.17
Dissociation Constants	8.71

Physical description & handling notes

• Administration of moxisylyte has shown to improve peripheral flow in occlusive arterial disease with little effect in blood pressure. There are reports of increases in cutaneous blood flow and skin temperature after local application of moxisylyte.

Documented Uses

• Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
• Agents causing contraction of the pupil of the eye. Some sources use the term miotics only for the parasympathomimetics but any drug used to induce miosis is included here.
• Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here.
• Drugs used to cause dilation of the blood vessels.
• G - Genito urinary system and sex hormones
• G04BE - Drugs used in erectile dysfunction

Synonyms

Moxisylyte; Thymoxamine; 54-32-0; Carlytene; Moxisilita; Acetoxythymoxamine; Moxisylytum; PW8QYA7KI0; (2-(4-Acetoxy-2-isopropyl-5-methylphenoxy)ethyl)dimethylamine; 6-Acetoxythymol 2-(dimethylamino)ethyl ether; DTXSID4023339; 4-[2-(dimethylamino)ethoxy]-2-methyl-5-(propan-2-yl)phenyl acetate; Thymoxyalcylamine; moxisilite; Erecnos; 4-(2-(dimethylamino)ethoxy)-2-methyl-5-(propan-2-yl)phenyl acetate

Frequently Asked Questions

What are the CAS number and molecular formula of moxisylyte hydrochloride?

CAS 964-52-3; molecular formula C16H25NO3; molecular weight — g/mol.

What other names is moxisylyte hydrochloride known by?

Moxisylyte, Thymoxamine, 54-32-0, Carlytene, Moxisilita, Acetoxythymoxamine.

What are the key physical properties of moxisylyte hydrochloride?

Boiling Point: 371ºC at 760 mmHg; Melting Point: 145ºC; Solubility: >47.4 ug/ml; LogP: 3.17.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.