奈帕芬胺

奈帕芬胺（CAS 78281-72-8）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

物理形态与操作说明

• Solid
• Low but quantifiable plasma concentrations of nepafenac and amfenac were observed in the majority of subjects 2 and 3 hours postdose, respectively, following bilateral topical ocular TID dosing of nepafenac ophthalmic suspension, 0.1%. The mean steady-state Cmax for nepafenac and for amfenac were 0.310 ± 0.104 ng/ml and 0.422 ± 0.121 ng/ml, respectively, following ocular administration.

这个物质在各数据库里的编号

数据库记载的用途

• For the treatment of pain and inflammation associated with cataract surgery.
• Breast Feeding; Lactation; Milk, Human; Analgesic Agents; Anti-inflammatory Agents, Nonsteroidal
• Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
• Mechanisms of Action [MoA] - Cyclooxygenase Inhibitors
• Chemical Structure [CS] - Anti-Inflammatory Agents, Non-Steroidal
• Established Pharmacologic Class [EPC] - Nonsteroidal Anti-inflammatory Drug

它在各数据库里的别名

Nepafenac; 78281-72-8; 2-(2-Amino-3-benzoylphenyl)acetamide; Nevanac; 2-Amino-3-benzoylbenzeneacetamide; AHR-9434; Ilevro; AL-6515; nepafenaco; AL 6515; nepafenacum; DTXSID0048638; 0J9L7J6V8C; CHEBI:75922; 2-[2-amino-3-(benzoyl)phenyl]acetamide; DTXCID7028564

计算机算出的分子描述符

数据库摘要

Nepafenac · CAS 78281-72-8 · C15H14N2O2. UNII 0J9L7J6V8C.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。