奈法唑酮

奈法唑酮（CAS 83366-66-9）的公开数据库记录，列此仅供独立核对。

物理形态与操作说明

• Solid
• Crystals from 2-propanol/heptane
• Crystals from 2-propanol, with slow cooling yields a polymorph. MP: 186.0-187.0 °C. Also reported as crystals from ethanol. Nonhygroscopic. MP. 175-177 °C. Freely solluble in chloroform; soluble in propylene gylcol; slightly soluble in polyethylene glycol, water /Nefazodone hydrchloride/
• 32.6 [ug/mL] (The mean of the results at pH 7.4)
• Stable under recommended storage conditions. /Nefazodone hydrochloride/
• 211.7 Ų [M+H]+ [CCS Type: TW; Method: Major Mix IMS/Tof Calibration Kit (Waters)]

公开数据库收录的理化数据

这个物质在各数据库里的编号

数据库记载的用途

• Antidepressive Agents, Second-Generation
• Consumption (g per capita) in the USA (2002): 0.0826
• Nefazodone (sold as Serzone, Nefadar) is a psychoactive drug and antidepressant. [wikipedia]
• Preparation: D. L. Temple, Jr., W. G. Lobeck, Jr., United States of America patent 4338317 (1982 to Mead Johnson).
• For the treatment of depression.
• Nefazodone is a serotoninergic modulating antidepressant that is used in therapy of depression, aggressive behavior and panic disorder. Nefazodone therapy has been associated with transient, usually asymptomatic elevations in serum aminotransferase levels and has been linked to several instances of clinically apparent acute liver injury some of which have been fatal.

它在各数据库里的别名

nefazodone; 83366-66-9; Nefazodona; Nefazodonum; Nefazodonum [Latin]; 1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one; 59H4FCV1TF; CHEBI:7494; 1-(3-(4-(3-Chlorpheyl-1-piperazinylpropyl)-3-ethyl-4,5-dihydro-4-(2-phenoxyethyl)-1,2,4-triazol-5-on; DTXSID2023357; Nefazodonum (Latin); 1-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-3-ethyl-4-(2-phenoxyethyl)-4,5-dihydro-1H-1,2,4-triazol-5-one; 3H-1,2,4-Triazol-3-one, 2,4-dihydro-2-3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-5-ethyl-4-(2-phenoxyethyl)-; 1-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-3-ethyl-4-(2-phenoxyethyl)-4,5-dihydro-1H-1,2,4-triazol-5-one; RefChem:57773; DTXCID203357

计算机算出的分子描述符

数据库摘要

Nefazodone · CAS 83366-66-9 · C25H32ClN5O2. UNII 59H4FCV1TF. 熔点: 83.5; 熔点: 83-84 °C; 熔点: 83 - 84 °C.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。