N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide

Description

N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide · CAS 158062-67-0 · C9H6F3N3O. UNII 9500W2Z53J. Melting Point: 157.5 °C; Solubility: In water, 5.2X10+3 mg/L at 20 °C; Density: 1.531 at 20 °C.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• White crystalline powder
• Odorless
• 150.8 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: Pesticides]
• Water dispersible granule
• F1785 GH 50 WG Insecticide (FMC Corp. Agricultural Products Group) Flonicamid 50%
• F1785 N 50 WG Insecticide (FMC Corp. Agricultural Products Group) Flonicamid 50%

GHS Hazard Classification

Documented Uses

• Foliar, selective aphicide; also effective against some other sucking insects. For use in Fruit, cereals, potatoes, cotton and vegetables ...
• Preparation: T. Toki et al., EP 580374; eidem, US 5360806 (both 1994 to Ishihara Sangyo Kaisha)
• In liver samples, the major components in male rat liver following 0.5 and 6 hours were flonicamid (51% and 27% total radioactive residues, respectively) and N-(4-trifluoromethylnicotinoyl)glycine (24% and 8% of total radioactive residues, respectively). 4-Trifluoromethylnicotinamide was 10% of total radioactive residues after 0.5 hours and 45% after 6 hours. In the rat biliary study, flonicamid was rapidly absorbed and excreted in the urine within 24 hours. ... The metabolic pathway of flonicamid in rats involves
• (14)C Flonicamid (radiolabelled = 98.5% pure; unlabelled = 99.7%) was used in 3 experiments in order to characterize metabolism in CRL:CD (SD)IGS BR rats: Study #1(Biliary): 4 rats/sex/dose were administered a single oral gavage dose of (14)C Flonicamid at 2 or 400 mg/kg, then terminated at 48 hours. Study #2 (Single-Dose Excretion): 3 or 5/sex/dose/time point were treated with a single oral gavage dose of (14)C Flonicamid at 2 or 400 mg/kg and terminated at 0.5, 6, 24 and 168 hours (2 mg/kg) or 3 (M), 1 (F), 14.5

Synonyms

Flonicamid; 158062-67-0; Aria; N-(cyanomethyl)-4-(trifluoromethyl)nicotinamide; 3-Pyridinecarboxamide, N-(cyanomethyl)-4-(trifluoromethyl)-; BELEAF; TURBINE; IKI-220; N-(Cyanomethyl)-4-(trifluoromethyl)-3-pyridinecarboxamide; 9500W2Z53J; n-cyanomethyl-4-trifluoromethylnicotinamide; DTXSID8034611; CHEBI:39291; n-cyanomethyl-4-(trifluoromethyl)nicotinamide; F-1785; RefChem:140716

Frequently Asked Questions

What are the CAS number and molecular formula of N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide?

CAS 158062-67-0; molecular formula C9H6F3N3O; molecular weight — g/mol.

What other names is N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide known by?

Flonicamid, 158062-67-0, Aria, N-(cyanomethyl)-4-(trifluoromethyl)nicotinamide, 3-Pyridinecarboxamide, N-(cyanomethyl)-4-(trifluoromethyl)-, BELEAF.

Is N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide classified as hazardous?

Hazard statements reported: H302.

What are the key physical properties of N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide?

Melting Point: 157.5 °C; Solubility: In water, 5.2X10+3 mg/L at 20 °C; Density: 1.531 at 20 °C; Vapor Pressure: 9.43X10-4 mPa /7.073X10-9 mm Hg/ at 20 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.