尼普地洛

Description

Nipradilol · CAS 81486-22-8 · C15H22N2O6. UNII FVM336I71Y.

Identification

CAS Registry Number	81486-22-8
PubChem CID	72006
Molecular formula	C15H22N2O6
IUPAC name	[8-[2-hydroxy-3-(propan-2-ylamino)propoxy]-3,4-dihydro-2H-chromen-3-yl] nitrate
UNII (FDA)	FVM336I71Y

Computed Descriptors

Molecular Weight	326.34
XLogP3	2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	7
Exact Mass	326.14778643
Monoisotopic Mass	326.14778643
Topological Polar Surface Area	106
Heavy Atom Count	23
Formal Charge	0

Documented Uses

• Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
• Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
• Drugs used to cause dilation of the blood vessels.

Synonyms

Nipradilol; Nipradolol; 81486-22-8; Hypadil; Nipradilolum; FVM336I71Y; K-351; 8-(2-Hydroxy-3-(isopropylamino)propoxy)-3-chromanol, 3-nitrate; DTXSID30868615; 2H-1-Benzopyran-3-ol, 3,4-dihydro-8-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, 3-nitrate; RefChem:927789; DTXCID60816705; 3,4-dihydro-8-(2-hydroxy-3--isopropylaminopropoxy)-3-nitroxy-2H-1-benzopyran; Hypadil (TN); [8-[2-hydroxy-3-(propan-2-ylamino)propoxy]-3,4-dihydro-2H-chromen-3-yl] nitrate; Hypadil; K 351; KT 210; Nipradilo

Frequently Asked Questions

What are the CAS number and molecular formula of Nipradilol?

CAS 81486-22-8; molecular formula C15H22N2O6; molecular weight — g/mol.

What other names is Nipradilol known by?

Nipradilol, Nipradolol, 81486-22-8, Hypadil, Nipradilolum, FVM336I71Y.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.