盐酸奥烯洛尔

Description

oxprenolol · CAS 6452-73-9 · C15H24ClNO3. UNII F4XSI7SNIU.

Identification

CAS Registry Number	6452-73-9
PubChem CID	71172
Molecular formula	C15H24ClNO3
IUPAC name	1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)propan-2-ol;hydrochloride
UNII (FDA)	F4XSI7SNIU

Computed Descriptors

Molecular Weight	301.81
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	9
Exact Mass	301.1444713
Monoisotopic Mass	301.1444713
Topological Polar Surface Area	50.7
Heavy Atom Count	20
Formal Charge	0
Complexity	246

Regulatory Status

GHS notification summary	20% (1 / 5)

GHS Hazard Classification

GHS notification summary	20% (1 / 5)
Reported hazard statements	H301 (60%), H302 (20%), H412 (20%)

Documented Uses

• Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
• Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
• Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here.
• Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here.
• Drugs used to cause dilation of the blood vessels.

Synonyms

Oxprenolol hydrochloride; 6452-73-9; Oxprenolol HCl; Slow-Trasicor; Ba-39089; DTXSID5021093; F4XSI7SNIU; 2-Propanol, 1-(o-allyloxyphenoxy)-3-isopropylamino-, hydrochloride; BA-39,089; 1-(o-Allyloxyphenoxy)-3-isopropylamino-2-propanol hydrochloride; DTXCID001093; 2-Propanol, 1-((1-methylethyl)amino)-3-(2-(2-propenyloxy)phenoxy)-, hydrochloride; Apsolox; Laracor; Paritane; Trasicor ret

Frequently Asked Questions

What are the CAS number and molecular formula of oxprenolol?

CAS 6452-73-9; molecular formula C15H24ClNO3; molecular weight — g/mol.

What other names is oxprenolol known by?

Oxprenolol hydrochloride, 6452-73-9, Oxprenolol HCl, Slow-Trasicor, Ba-39089, DTXSID5021093.

Is oxprenolol classified as hazardous?

20% of GHS notifications report no hazard classification (1 of 5).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.