奥昔嘌呤醇

Description

Oxipurinol · CAS 2465-59-0 · C5H4N4O2. UNII G97OZE5068. Melting Point: 300 °C.

Identification

CAS Registry Number	2465-59-0
PubChem CID	135398752
Molecular formula	C5H4N4O2
IUPAC name	1,7-dihydropyrazolo[5,4-d]pyrimidine-4,6-dione
UNII (FDA)	G97OZE5068

Computed Descriptors

Molecular Weight	152.11
XLogP3	-0.9
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	0
Exact Mass	152.03342538
Monoisotopic Mass	152.03342538
Topological Polar Surface Area	86.9
Heavy Atom Count	11
Formal Charge	0

Physical & Chemical Properties

Melting Point	300 °C

Physical description & handling notes

• Solid
• 122.3 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID4035209]
• 120.1 Ų [M-H]- [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]
• 126.7 Ų [M+H]+ [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]

GHS Hazard Classification

Reported hazard statements	H315 (97.6%), H319 (97.6%), H335 (97.6%)

Documented Uses

• Intended for the treatment of congestive heart failure and hyperuricemia.
• Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
• Oxypurinol inhibits the enzyme xanthine oxidase, blocking the conversion of the oxypurines hypoxanthine and xanthine to uric acid. Elevated concentrations of oxypurine and oxypurine inhibition of xanthine oxidase through negative feedback results in a decrease in the concentrations of uric acid in the blood and urine. Oxypurinol also facilitates the incorporation of hypoxanthine and xanthine into DNA and RNA, resulting in further reductions of serum uric acid concentrations.

Synonyms

Oxypurinol; 2465-59-0; Oxipurinol; 1H-Pyrazolo[3,4-d]pyrimidine-4,6-diol; Alloxanthine; Oxoallopurinol; DHPP; 1H-Pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione; NSC-76239; Ossipurinolo; Oxipurinolum; DTXSID4035209; CHEBI:28315; 1H-Pyrazolo(3,4-d)pyrimidine-4,6-diol; G97OZE5068; 1,2-dihydropyrazolo[3,4-d]pyrimidine-4,6-dione

Frequently Asked Questions

What are the CAS number and molecular formula of Oxipurinol?

CAS 2465-59-0; molecular formula C5H4N4O2; molecular weight — g/mol.

What other names is Oxipurinol known by?

Oxypurinol, 2465-59-0, Oxipurinol, 1H-Pyrazolo[3,4-d]pyrimidine-4,6-diol, Alloxanthine, Oxoallopurinol.

Is Oxipurinol classified as hazardous?

Hazard statements reported: H315, H319, H335.

What are the key physical properties of Oxipurinol?

Melting Point: 300 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.