prednisolone acetate

Description

prednisolone acetate · CAS 52-21-1 · C23H30O6. UNII 8B2807733D. Melting Point: 238; LogP: 1.332; LogP: 2.4.

Identification

CAS Registry Number	52-21-1
PubChem CID	5834
Molecular formula	C23H30O6
IUPAC name	[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
UNII (FDA)	8B2807733D

Computed Descriptors

Molecular Weight	402.5
XLogP3	2.4
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	4
Exact Mass	402.20423867
Monoisotopic Mass	402.20423867
Topological Polar Surface Area	101
Heavy Atom Count	29
Formal Charge	0

Physical & Chemical Properties

Melting Point	238
LogP	1.332
LogP	2.4

Physical description & handling notes

• 194 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Regulatory Status

GHS notification summary	1.1% (1 / 93)

GHS Hazard Classification

GHS notification summary	1.1% (1 / 93)
Reported hazard statements	H300 (40.9%), H319 (11.8%), H360 (34.4%), H361 (16.1%), H373 (37.6%)

Documented Uses

• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Prednisolone acetate is indicated as an anti-inflammatory or immunosuppressive agent for allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, or infectious conditions. Prednisolone acetate is also indicated in organ transplant patients, as well as endocrine or neoplastic conditions.
• Avoid excessive or chronic alcohol consumption. Alcohol may cause gastric irritation.
• Take with food. Food reduces gastrointestinal irritation.
• Substances that reduce or suppress INFLAMMATION.
• A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.

Synonyms

prednisolone acetate; 52-21-1; Prednisolone 21-acetate; Omnipred; Econopred; Pricortin; Meticortelone acetate; Pred Mild; Pred Forte; Flo-Pred; DTXSID3023502; Prednisoloni acetas; NSC-10966; 11beta,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-acetate; DTXCID103502; 8B2807733D

Frequently Asked Questions

What are the CAS number and molecular formula of prednisolone acetate?

CAS 52-21-1; molecular formula C23H30O6; molecular weight — g/mol.

What other names is prednisolone acetate known by?

prednisolone acetate, 52-21-1, Prednisolone 21-acetate, Omnipred, Econopred, Pricortin.

Is prednisolone acetate classified as hazardous?

1.1% of GHS notifications report no hazard classification (1 of 93).

What are the key physical properties of prednisolone acetate?

Melting Point: 238; LogP: 1.332; LogP: 2.4.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.