帕米膦酸

帕米膦酸（CAS 40391-99-9）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

物理形态与操作说明

• Solid
• Pamidronic acid is a second generation, nitrogen containing bisphosphonate that inhibits osteoclast mediated bone loss It has a wide therapeutic index and a long duration of action as it can be given every 3-4 weeks for certain indications. Patients should be counselled regarding the risk of elevated blood urea nitrogen, renal tubular necrosis, and nephrotoxicity.

公开数据库收录的理化数据

这个物质在各数据库里的编号

数据库记载的用途

• Use (kg; approx.) in Germany (2009): >10
• Consumption (g per capita; approx.) in Germany (2009): 0.000122
• Consumption (g per capita) in the USA (2002): 5.1e-05
• Pamidronate is in a class of drugs called bisphosphonates. Pamidronate reduces breakdown of the bones. Pamidronate is used in the treatment of Paget's disease of bone; to reduce high levels of calcium in the blood associated with malignancy (cancer); and to reduce the breakdown of bone due to metastases of breast cancer or multiple myeloma. For the treatment of moderate or severe hypercalcemia associated with malignancy
• Pamidronate is indicated to treat moderate to severe hypercalcemia of malignancy, moderate to severe Paget's disease of bone, osteolytic bone metastases of breast cancer, and osteolytic lesions of multiple myeloma.
• Pamidronate belongs to the drug class known as bisphosphonates, whose therapeutic value stems from their ability to inhibit osteoclast-mediated bone resorption.

它在各数据库里的别名

PAMIDRONIC ACID; pamidronate; 40391-99-9; Amidronate; Acide pamidronique; (3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid; Acido pamidronico; Acidum pamidronicum; Ribodroat; (3-Amino-1-hydroxypropylidene)bisphosphonic acid; DTXSID4023414; AHPrBP; OYY3447OMC; (3-Amino-1-hydroxypropylidene)diphosphonic acid; DTXCID003414; (3-amino-1-hydroxypropylidene)-1,1-biphosphonate

计算机算出的分子描述符

数据库摘要

Pamidronic acid · CAS 40391-99-9 · C3H11NO7P2. UNII OYY3447OMC. 熔点: 254-262; 溶解度: 1.58e+01 g/L; LogP: -4.7.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。