盐酸苯乙双胍

Description

phenformin hydrochloride · CAS 834-28-6 · C10H15N5.ClH. UNII 91XC93EU03. Melting Point: 347 to 352 °F (NTP, 1992).

Identification

CAS Registry Number	834-28-6
PubChem CID	13266
Molecular formula	C10H15N5.ClH
IUPAC name	1-(diaminomethylidene)-2-(2-phenylethyl)guanidine;hydrochloride
UNII (FDA)	91XC93EU03

Computed Descriptors

Molecular Weight	241.72
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	4
Exact Mass	241.1094232
Monoisotopic Mass	241.1094232
Topological Polar Surface Area	103
Heavy Atom Count	16
Formal Charge	0
Complexity	236

Physical & Chemical Properties

Melting Point	347 to 352 °F (NTP, 1992)

Physical description & handling notes

• Phenformin hydrochloride appears as white solid or powder. Formerly used as an anti-diabetic drug. Toxic (causes lactic acidosis.
• greater than or equal to 100 mg/mL at 70 °F (NTP, 1992)
• >36.3 [ug/mL] (The mean of the results at pH 7.4)
• 145.7 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H302 (100%)

Synonyms

PHENFORMIN HYDROCHLORIDE; Meltrol-50; Debei; Phenformin, hydrochloride; Phenformin HCl No. 9113; CCRIS 4857; DTXSID0021121; Phenoformine hydrochloride; EINECS 212-637-3; NSC 23100; NSC-23100; 1-Fenetilbiguanide cloridrato; UNII-91XC93EU03; 1beta-Phenylethylbiguanide hydrochloride; 1-Fenetilbiguanide cloridrato [Italian]; Phenformin hydrochloride [USP]

Frequently Asked Questions

What are the CAS number and molecular formula of phenformin hydrochloride?

CAS 834-28-6; molecular formula C10H15N5.ClH; molecular weight — g/mol.

What other names is phenformin hydrochloride known by?

PHENFORMIN HYDROCHLORIDE, Meltrol-50, Debei, Phenformin, hydrochloride, Phenformin HCl No. 9113, CCRIS 4857.

Is phenformin hydrochloride classified as hazardous?

Hazard statements reported: H302.

What are the key physical properties of phenformin hydrochloride?

Melting Point: 347 to 352 °F (NTP, 1992).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.